node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFC87852.1 | EFC89290.1 | NEIMUCOT_05768 | NEIMUCOT_04193 | KEGG: nme:NMB1807 0. penicillin-binding protein 1A (penicillin-insensitive transglycosylase / penicillin-sensitive transpeptidase) K05366. | Transglycosylase SLT domain protein; KEGG: ngo:NGO0608 1.9e-178 putative murein transglycosylase / nitrite reductase transcriptional regulator K01238; Psort location: OuterMembrane, score: 9.49. | 0.475 |
EFC87852.1 | mpl | NEIMUCOT_05768 | NEIMUCOT_04755 | KEGG: nme:NMB1807 0. penicillin-binding protein 1A (penicillin-insensitive transglycosylase / penicillin-sensitive transpeptidase) K05366. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.452 |
EFC87852.1 | nagZ | NEIMUCOT_05768 | NEIMUCOT_04313 | KEGG: nme:NMB1807 0. penicillin-binding protein 1A (penicillin-insensitive transglycosylase / penicillin-sensitive transpeptidase) K05366. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.478 |
EFC88463.1 | EFC89912.1 | NEIMUCOT_05135 | NEIMUCOT_03712 | AmpG-related permease; KEGG: eci:UTI89_C0457 3.1e-73 ampG; AmpG muropeptide MFS transporter K08218; Psort location: CytoplasmicMembrane, score: 10.00. | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | 0.430 |
EFC88463.1 | nagZ | NEIMUCOT_05135 | NEIMUCOT_04313 | AmpG-related permease; KEGG: eci:UTI89_C0457 3.1e-73 ampG; AmpG muropeptide MFS transporter K08218; Psort location: CytoplasmicMembrane, score: 10.00. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.468 |
EFC89285.1 | nagZ | NEIMUCOT_04188 | NEIMUCOT_04313 | LD-carboxypeptidase; KEGG: ngo:NGO1274 1.4e-95 hypothetical protein K01297. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.410 |
EFC89290.1 | EFC87852.1 | NEIMUCOT_04193 | NEIMUCOT_05768 | Transglycosylase SLT domain protein; KEGG: ngo:NGO0608 1.9e-178 putative murein transglycosylase / nitrite reductase transcriptional regulator K01238; Psort location: OuterMembrane, score: 9.49. | KEGG: nme:NMB1807 0. penicillin-binding protein 1A (penicillin-insensitive transglycosylase / penicillin-sensitive transpeptidase) K05366. | 0.475 |
EFC89290.1 | nagZ | NEIMUCOT_04193 | NEIMUCOT_04313 | Transglycosylase SLT domain protein; KEGG: ngo:NGO0608 1.9e-178 putative murein transglycosylase / nitrite reductase transcriptional regulator K01238; Psort location: OuterMembrane, score: 9.49. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.432 |
EFC89405.1 | EFC89407.1 | NEIMUCOT_04310 | NEIMUCOT_04312 | Peptidase Do; KEGG: nme:NMB0532 2.4e-192 htrA; protease DO; Psort location: Periplasmic, score: 9.44; Belongs to the peptidase S1C family. | Na+/H+ antiporter family protein; KEGG: net:Neut_0846 0.0035 protein-disulfide reductase K05905; Psort location: CytoplasmicMembrane, score: 10.00. | 0.449 |
EFC89405.1 | nagZ | NEIMUCOT_04310 | NEIMUCOT_04313 | Peptidase Do; KEGG: nme:NMB0532 2.4e-192 htrA; protease DO; Psort location: Periplasmic, score: 9.44; Belongs to the peptidase S1C family. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.426 |
EFC89407.1 | EFC89405.1 | NEIMUCOT_04312 | NEIMUCOT_04310 | Na+/H+ antiporter family protein; KEGG: net:Neut_0846 0.0035 protein-disulfide reductase K05905; Psort location: CytoplasmicMembrane, score: 10.00. | Peptidase Do; KEGG: nme:NMB0532 2.4e-192 htrA; protease DO; Psort location: Periplasmic, score: 9.44; Belongs to the peptidase S1C family. | 0.449 |
EFC89407.1 | nagZ | NEIMUCOT_04312 | NEIMUCOT_04313 | Na+/H+ antiporter family protein; KEGG: net:Neut_0846 0.0035 protein-disulfide reductase K05905; Psort location: CytoplasmicMembrane, score: 10.00. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.519 |
EFC89638.1 | mpl | NEIMUCOT_04056 | NEIMUCOT_04755 | Phosphotransferase enzyme family; KEGG: bte:BTH_I0574 1.5e-73 hypothetical protein. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.489 |
EFC89638.1 | nagZ | NEIMUCOT_04056 | NEIMUCOT_04313 | Phosphotransferase enzyme family; KEGG: bte:BTH_I0574 1.5e-73 hypothetical protein. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.934 |
EFC89912.1 | EFC88463.1 | NEIMUCOT_03712 | NEIMUCOT_05135 | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | AmpG-related permease; KEGG: eci:UTI89_C0457 3.1e-73 ampG; AmpG muropeptide MFS transporter K08218; Psort location: CytoplasmicMembrane, score: 10.00. | 0.430 |
EFC89912.1 | anmK | NEIMUCOT_03712 | NEIMUCOT_04264 | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.454 |
EFC89912.1 | mpl | NEIMUCOT_03712 | NEIMUCOT_04755 | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.499 |
EFC89912.1 | nagZ | NEIMUCOT_03712 | NEIMUCOT_04313 | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.510 |
anmK | EFC89912.1 | NEIMUCOT_04264 | NEIMUCOT_03712 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramoyl-L-alanine amidase; KEGG: azo:azo3350 5.3e-55 ampD2; N-acetyl-anhydromuramyl-L-alanine amidase K01446; Psort location: Cytoplasmic, score: 9.97. | 0.454 |
anmK | nagZ | NEIMUCOT_04264 | NEIMUCOT_04313 | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glycosyl hydrolase family 3 N-terminal domain protein; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.817 |