STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
holBKEGG: nma:NMA0980 6.6e-119 holB; putative DNA polymerase III, delta' subunit K02341. (365 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
 
 0.999
EFC89233.1
KEGG: nma:NMA0632 0. dnaE; DNA polymerase III alpha subunit K02337; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.997
EFC87276.1
KEGG: nme:NMB1443 5.0e-201 dnaX; DNA polymerase III subunits gamma and tau K00961.
 
 
 
 0.991
holA
KEGG: nme:NMB0708 3.0e-75 DNA polymerase III, delta subunit K02340; Psort location: Cytoplasmic, score: 8.96; overlaps another CDS with the same product name.
  
 
 0.977
holC
KEGG: nme:NMB1568 1.0e-49 DNA polymerase holoenzyme chi subunit, putative K02339.
  
 
 
 0.965
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 0.948
EFC89990.1
Exonuclease; KEGG: nme:NMB1451 1.1e-127 DNA polymerase III, epsilon subunit K02342; Psort location: Cytoplasmic, score: 8.96.
  
  0.934
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
   
  0.920
EFC88185.1
ATP-dependent DNA ligase domain protein; KEGG: nma:NMA0388 4.7e-134 DNA ligase K01971.
   
 0.885
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.827
Your Current Organism:
Neisseria mucosa
NCBI taxonomy Id: 546266
Other names: N. mucosa ATCC 25996, Neisseria mucosa ATCC 25996, Neisseria mucosa str. ATCC 25996, Neisseria mucosa strain ATCC 25996
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