STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lapBTetratricopeptide repeat protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa)    
Predicted Functional Partners:
EFC87378.1
Hypothetical protein.
 
   
 0.883
lptD
LPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
   
 0.668
LptF
Permease, YjgP/YjgQ family; Psort location: CytoplasmicMembrane, score: 10.00; overlaps another CDS with the same product name.
  
     0.639
EFC89684.1
Hypothetical protein; KEGG: reh:H16_A2398 1.8e-27 arnT; 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family K00754; Psort location: CytoplasmicMembrane, score: 10.00.
  
     0.601
EFC87420.1
HemX; KEGG: ngo:NGO0360 8.3e-144 uroporphyrin-III C-methyltransferase K02496.
  
     0.575
cvpA
CvpA family protein; Psort location: CytoplasmicMembrane, score: 9.46.
  
   
 0.551
lptE
Rare lipoprotein B family protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
  
   
 0.515
ftsB
Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
 
     0.478
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
     0.477
EFC87859.1
Hypothetical protein; KEGG: mst:Msp_0485 0.00090 apgM1; ApgM1 K01834.
  
     0.472
Your Current Organism:
Neisseria mucosa
NCBI taxonomy Id: 546266
Other names: N. mucosa ATCC 25996, Neisseria mucosa ATCC 25996, Neisseria mucosa str. ATCC 25996, Neisseria mucosa strain ATCC 25996
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.