node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFE28384.1 | recX | HMPREF0389_00299 | HMPREF0389_00405 | Peptidase M16 inactive domain protein. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.554 |
EFE28547.1 | recX | HMPREF0389_00463 | HMPREF0389_00405 | Hypothetical protein; Belongs to the 5'(3')-deoxyribonucleotidase family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.563 |
EFE28547.1 | secG | HMPREF0389_00463 | HMPREF0389_00563 | Hypothetical protein; Belongs to the 5'(3')-deoxyribonucleotidase family. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.418 |
cinA | recA | HMPREF0389_01652 | HMPREF0389_00356 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.721 |
cinA | recX | HMPREF0389_01652 | HMPREF0389_00405 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.548 |
cinA | uvrB | HMPREF0389_01652 | HMPREF0389_00407 | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.436 |
purD | recA | HMPREF0389_00494 | HMPREF0389_00356 | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.684 |
purD | recX | HMPREF0389_00494 | HMPREF0389_00405 | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.578 |
purD | typA | HMPREF0389_00494 | HMPREF0389_00404 | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | GTP-binding protein TypA. | 0.533 |
radA | recA | HMPREF0389_01642 | HMPREF0389_00356 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.752 |
radA | recX | HMPREF0389_01642 | HMPREF0389_00405 | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.684 |
recA | cinA | HMPREF0389_00356 | HMPREF0389_01652 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | 0.721 |
recA | purD | HMPREF0389_00356 | HMPREF0389_00494 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family. | 0.684 |
recA | radA | HMPREF0389_00356 | HMPREF0389_01642 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.752 |
recA | recX | HMPREF0389_00356 | HMPREF0389_00405 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | 0.919 |
recA | uvrA | HMPREF0389_00356 | HMPREF0389_00406 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.486 |
recA | uvrB | HMPREF0389_00356 | HMPREF0389_00407 | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.542 |
recX | EFE28384.1 | HMPREF0389_00405 | HMPREF0389_00299 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Peptidase M16 inactive domain protein. | 0.554 |
recX | EFE28547.1 | HMPREF0389_00405 | HMPREF0389_00463 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Hypothetical protein; Belongs to the 5'(3')-deoxyribonucleotidase family. | 0.563 |
recX | cinA | HMPREF0389_00405 | HMPREF0389_01652 | Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family. | Competence/damage-inducible domain protein CinA; Belongs to the CinA family. | 0.548 |