node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFE28388.1 | ddl | HMPREF0389_00303 | HMPREF0389_00532 | Putative stage V sporulation protein D. | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.832 |
EFE28388.1 | mraY | HMPREF0389_00303 | HMPREF0389_00305 | Putative stage V sporulation protein D. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.962 |
EFE28388.1 | murA | HMPREF0389_00303 | HMPREF0389_00075 | Putative stage V sporulation protein D. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.802 |
EFE28388.1 | murB | HMPREF0389_00303 | HMPREF0389_01258 | Putative stage V sporulation protein D. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.663 |
EFE28388.1 | murC | HMPREF0389_00303 | HMPREF0389_00592 | Putative stage V sporulation protein D. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.876 |
EFE28388.1 | murD | HMPREF0389_00303 | HMPREF0389_00306 | Putative stage V sporulation protein D. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.964 |
EFE28388.1 | murE | HMPREF0389_00303 | HMPREF0389_00596 | Putative stage V sporulation protein D. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Belongs to the MurCDEF family. MurE subfamily. | 0.867 |
EFE28388.1 | murF | HMPREF0389_00303 | HMPREF0389_00304 | Putative stage V sporulation protein D. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.954 |
EFE28388.1 | murG | HMPREF0389_00303 | HMPREF0389_00308 | Putative stage V sporulation protein D. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.912 |
EFE28680.2 | murE | HMPREF0389_00597 | HMPREF0389_00596 | Hypothetical protein. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Belongs to the MurCDEF family. MurE subfamily. | 0.851 |
ddl | EFE28388.1 | HMPREF0389_00532 | HMPREF0389_00303 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Putative stage V sporulation protein D. | 0.832 |
ddl | mraY | HMPREF0389_00532 | HMPREF0389_00305 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.707 |
ddl | murA | HMPREF0389_00532 | HMPREF0389_00075 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.620 |
ddl | murB | HMPREF0389_00532 | HMPREF0389_01258 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.993 |
ddl | murC | HMPREF0389_00532 | HMPREF0389_00592 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.983 |
ddl | murD | HMPREF0389_00532 | HMPREF0389_00306 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.816 |
ddl | murE | HMPREF0389_00532 | HMPREF0389_00596 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Belongs to the MurCDEF family. MurE subfamily. | 0.683 |
ddl | murF | HMPREF0389_00532 | HMPREF0389_00304 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddl | murG | HMPREF0389_00532 | HMPREF0389_00308 | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.799 |
mraY | EFE28388.1 | HMPREF0389_00305 | HMPREF0389_00303 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Putative stage V sporulation protein D. | 0.962 |