node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFE28137.2 | rnj | HMPREF0389_00050 | HMPREF0389_00963 | FtsK/SpoIIIE family protein; Belongs to the FtsK/SpoIIIE/SftA family. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.722 |
EFE28137.2 | topA | HMPREF0389_00050 | HMPREF0389_00129 | FtsK/SpoIIIE family protein; Belongs to the FtsK/SpoIIIE/SftA family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.442 |
EFE28594.1 | rnj | HMPREF0389_00511 | HMPREF0389_00963 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.565 |
EFE28594.1 | rny | HMPREF0389_00511 | HMPREF0389_00503 | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. | 0.413 |
EFE29039.1 | EFE29040.2 | HMPREF0389_00961 | HMPREF0389_00962 | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Peptidase, M50 family. | 0.790 |
EFE29039.1 | rnj | HMPREF0389_00961 | HMPREF0389_00963 | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.563 |
EFE29039.1 | scpB | HMPREF0389_00961 | HMPREF0389_00960 | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.999 |
EFE29040.2 | EFE29039.1 | HMPREF0389_00962 | HMPREF0389_00961 | Peptidase, M50 family. | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.790 |
EFE29040.2 | rnj | HMPREF0389_00962 | HMPREF0389_00963 | Peptidase, M50 family. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.563 |
EFE29040.2 | scpB | HMPREF0389_00962 | HMPREF0389_00960 | Peptidase, M50 family. | Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves. | 0.788 |
guaA | pnp | HMPREF0389_01060 | HMPREF0389_00334 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.702 |
guaA | rnj | HMPREF0389_01060 | HMPREF0389_00963 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.408 |
guaA | topA | HMPREF0389_01060 | HMPREF0389_00129 | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.466 |
pnp | guaA | HMPREF0389_00334 | HMPREF0389_01060 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.702 |
pnp | rnj | HMPREF0389_00334 | HMPREF0389_00963 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | 0.488 |
pnp | rny | HMPREF0389_00334 | HMPREF0389_00503 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | YmdA/YtgF family protein; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family. | 0.851 |
rnj | EFE28137.2 | HMPREF0389_00963 | HMPREF0389_00050 | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | FtsK/SpoIIIE family protein; Belongs to the FtsK/SpoIIIE/SftA family. | 0.722 |
rnj | EFE28594.1 | HMPREF0389_00963 | HMPREF0389_00511 | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.565 |
rnj | EFE29039.1 | HMPREF0389_00963 | HMPREF0389_00961 | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. | 0.563 |
rnj | EFE29040.2 | HMPREF0389_00963 | HMPREF0389_00962 | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. | Peptidase, M50 family. | 0.563 |