STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFE29191.1HAD hydrolase, family IB. (250 aa)    
Predicted Functional Partners:
EFE29192.1
Hypothetical protein.
       0.741
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.574
EFE27859.2
Hypothetical protein.
  
     0.527
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
  
  
 0.509
purD
Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family.
  
  
 0.488
EFE29189.1
Phosphorylase family.
       0.487
EFE28448.1
Tetratricopeptide repeat protein.
 
     0.473
EFE29193.1
Hypothetical protein.
       0.461
EFE28638.2
Penicillin-binding protein, transpeptidase domain protein.
  
     0.454
EFE28203.1
Putative histidinol-phosphate transaminase.
  
  
 0.427
Your Current Organism:
Filifactor alocis
NCBI taxonomy Id: 546269
Other names: F. alocis ATCC 35896, Filifactor alocis ATCC 35896, Filifactor alocis str. ATCC 35896, Filifactor alocis strain ATCC 35896
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