Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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nrdGAnaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (167 aa)    
Predicted Functional Partners:
nrdD
COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: elm:ELI_3633 anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone; PRIAM: Ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; IMG reference gene:2504587655; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase.
 
 
 0.996
queD
Queuosine biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: drm:Dred_1754 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Queuosine biosynthesis protein QueD; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504586623; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
  
  
 0.795
queF
NADPH-dependent 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
  
  
 0.712
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.665
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
  
  
 0.650
AEB99323.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
     
 0.461
AEC00002.1
InterPro IPR001440:IPR013105:IPR019734; KEGG: pmt:PMT0296 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Putative TPR repeat-containing domain protein; IMG reference gene:2504586521; PFAM: Tetratricopeptide repeat.
  
    0.410
AEC01088.1
COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: gsu:GSU2357 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel; IMG reference gene:2504587656; PFAM: Mechanosensitive ion channel.
       0.409
AEB99998.1
CoA-substrate-specific enzyme activase; COGs: COG3581 conserved hypothetical protein; InterPro IPR018709:IPR008275:IPR010327:IPR002731; KEGG: ccv:CCV52592_1797 CoA-substrate-specific enzyme activase domain-containing protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; 2-hydroxyglutaryl-CoA dehydratase, D-component; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: BadF/BadG/BcrA/BcrD ATPase family protein; TIGRFAM: CoA enzyme activase; IMG reference gene:2504586518; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase u [...]
       0.401
Your Current Organism:
Selenomonas sputigena
NCBI taxonomy Id: 546271
Other names: S. sputigena ATCC 35185, Selenomonas sputigena ATCC 35185, Selenomonas sputigena DSM 20758, Selenomonas sputigena HMP_JCVI_SC0180, Selenomonas sputigena str. ATCC 35185, Selenomonas sputigena strain ATCC 35185
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