node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
efp | ilvD | FUSPEROL_02401 | FUSPEROL_01566 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | KEGG: tte:TTE0020 8.9e-189 ilvD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family. | 0.708 |
ilvA-2 | ilvB | FUSPEROL_01567 | FUSPEROL_01568 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 0.941 |
ilvA-2 | ilvC | FUSPEROL_01567 | FUSPEROL_01575 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.674 |
ilvA-2 | ilvD | FUSPEROL_01567 | FUSPEROL_01566 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | KEGG: tte:TTE0020 8.9e-189 ilvD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family. | 0.821 |
ilvA-2 | ilvN | FUSPEROL_01567 | FUSPEROL_01569 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | Acetolactate synthase, small subunit; KEGG: mma:MM_0669 5.1e-35 ilvH; acetolactate synthase 3 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. | 0.955 |
ilvA-2 | leuA | FUSPEROL_01567 | FUSPEROL_01570 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.676 |
ilvA-2 | leuB | FUSPEROL_01567 | FUSPEROL_01573 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.693 |
ilvA-2 | leuC | FUSPEROL_01567 | FUSPEROL_01571 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.606 |
ilvA-2 | leuD | FUSPEROL_01567 | FUSPEROL_01572 | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.714 |
ilvB | ilvA-2 | FUSPEROL_01568 | FUSPEROL_01567 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 0.941 |
ilvB | ilvC | FUSPEROL_01568 | FUSPEROL_01575 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.971 |
ilvB | ilvD | FUSPEROL_01568 | FUSPEROL_01566 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | KEGG: tte:TTE0020 8.9e-189 ilvD; dihydroxy-acid dehydratase; K01687 dihydroxy-acid dehydratase; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family. | 0.988 |
ilvB | ilvE | FUSPEROL_01568 | FUSPEROL_00625 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | Branched-chain-amino-acid transaminase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.582 |
ilvB | ilvN | FUSPEROL_01568 | FUSPEROL_01569 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | Acetolactate synthase, small subunit; KEGG: mma:MM_0669 5.1e-35 ilvH; acetolactate synthase 3 regulatory subunit K01653; Psort location: Cytoplasmic, score: 8.96. | 0.999 |
ilvB | leuA | FUSPEROL_01568 | FUSPEROL_01570 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.883 |
ilvB | leuB | FUSPEROL_01568 | FUSPEROL_01573 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. | 0.863 |
ilvB | leuC | FUSPEROL_01568 | FUSPEROL_01571 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.786 |
ilvB | leuD | FUSPEROL_01568 | FUSPEROL_01572 | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.817 |
ilvC | ilvA-2 | FUSPEROL_01575 | FUSPEROL_01567 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | KEGG: fnu:FN1411 1.4e-160 threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. | 0.674 |
ilvC | ilvB | FUSPEROL_01575 | FUSPEROL_01568 | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | KEGG: hor:Hore_10830 1.8e-167 acetolactate synthase, large subunit, biosynthetic type K01652. | 0.971 |