STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFW88998.1Phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)    
Predicted Functional Partners:
SFW89511.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.791
SFW89002.1
GrpB domain, predicted nucleotidyltransferase, UPF0157 family.
       0.732
SFW89868.1
Pyruvate kinase; Manually curated; Belongs to the pyruvate kinase family.
  
 0.723
SFW71464.1
FAD/FMN-containing dehydrogenase.
   
 0.691
SFW85894.1
FAD/FMN-containing dehydrogenase.
   
 0.691
gpmA
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
   
 0.690
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 0.674
SFW81171.1
Formate dehydrogenase major subunit; Contains selenocysteine; manually curated; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.661
SFW91699.1
D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
  
 
0.643
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.635
Your Current Organism:
Amycolatopsis australiensis
NCBI taxonomy Id: 546364
Other names: A. australiensis, Amycolatopsis australiensis Tan et al. 2006, Amycolatopsis sp. GY048, Amycolatopsis sp. GY049, Amycolatopsis sp. GY056, Amycolatopsis sp. GY064, Amycolatopsis sp. GY269, Amycolatopsis sp. GY276, Amycolatopsis sp. GY286, DSM 44671, JCM 15587, NCIMB 14142, strain GY048
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