| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACO46932.2 | ndk | Deide_19360 | Deide_07830 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |
| adk | gmk | Deide_18740 | Deide_23190 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.687 |
| adk | ndk | Deide_18740 | Deide_07830 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.967 |
| adk | pyrG | Deide_18740 | Deide_16230 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.400 |
| adk | pyrH | Deide_18740 | Deide_13200 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative Uridylate kinase (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 0.538 |
| adk | rpsG | Deide_18740 | Deide_19000 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.938 |
| adk | rpsJ | Deide_18740 | Deide_18960 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.795 |
| adk | rpsL | Deide_18740 | Deide_19010 | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Putative 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.641 |
| cmk | gmk | Deide_22220 | Deide_23190 | Putative cytidylate kinase (Cytidine monophosphate kinase) (Deoxycytidine kinase) (Deoxycytidylate kinase). | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | 0.477 |
| cmk | ndk | Deide_22220 | Deide_07830 | Putative cytidylate kinase (Cytidine monophosphate kinase) (Deoxycytidine kinase) (Deoxycytidylate kinase). | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.932 |
| cmk | pyrG | Deide_22220 | Deide_16230 | Putative cytidylate kinase (Cytidine monophosphate kinase) (Deoxycytidine kinase) (Deoxycytidylate kinase). | Putative CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.507 |
| dcd | ndk | Deide_16640 | Deide_07830 | Putative deoxycytidine triphosphate deaminase (dCTP deaminase); Catalyzes the deamination of dCTP to dUTP. | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.926 |
| gmk | adk | Deide_23190 | Deide_18740 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.687 |
| gmk | cmk | Deide_23190 | Deide_22220 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative cytidylate kinase (Cytidine monophosphate kinase) (Deoxycytidine kinase) (Deoxycytidylate kinase). | 0.477 |
| gmk | ndk | Deide_23190 | Deide_07830 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.924 |
| gmk | pyrG | Deide_23190 | Deide_16230 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative CTP synthase (UTP--ammonia ligase) (CTP synthetase); Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.487 |
| gmk | pyrH | Deide_23190 | Deide_13200 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative Uridylate kinase (UMP kinase); Catalyzes the reversible phosphorylation of UMP to UDP. | 0.744 |
| gmk | rpsL | Deide_23190 | Deide_19010 | Putative guanylate kinase (GMP kinase); Essential for recycling GMP and indirectly, cGMP. | Putative 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. | 0.409 |
| ndk | ACO46932.2 | Deide_07830 | Deide_19360 | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.924 |
| ndk | adk | Deide_07830 | Deide_18740 | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.967 |