Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACO45845.1Putative Acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase); Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)    
Predicted Functional Partners:
ACO45843.1
Putative Fatty acid oxidation complex subunit alpha.
 0.999
ACO46696.1
Putative 3-hydroxyacyl-CoA dehydrogenase, NAD-binding, precursor.
 
 0.998
ACO44968.1
Putative 3-hydroxybutyryl-CoA dehydrogenase (Beta- hydroxybutyryl-CoA dehydrogenase) (BHBD).
 
 0.971
ACO46681.1
Putative 3-oxoacid CoA-transferase (Succinyl-CoA:3-ketoacid-CoA transferase).
  
 
 0.955
ACO45897.1
Putative acyl-CoA dehydrogenase.
  
 0.951
ACO47357.1
Putative phosphate acetyltransferase (phosphoacylase) (phosphotransacetylase); Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
    
 0.934
ACO46439.1
Putative 3-oxoacid CoA-transferase, subunit B (Succinyl-CoA:3-ketoacid-CoA transferase).
  
 
 0.933
ACO46341.1
Putative Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.924
leuA
Putative 2-isopropylmalate synthase (Isopropylmalate synthase); Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.924
acsA
Putative acetate--CoA ligase (Acyl-activating enzyme, Acetyl-activating enzyme); Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.921
Your Current Organism:
Deinococcus deserti
NCBI taxonomy Id: 546414
Other names: D. deserti VCD115, Deinococcus deserti VCD115, Deinococcus deserti str. VCD115, Deinococcus deserti strain VCD115
Server load: low (18%) [HD]