Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
panBPutative 3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase); Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa)    
Predicted Functional Partners:
panC
Putative pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.997
ilvD
Putative dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
     
 0.927
panD
Putative aspartate 1-decarboxylase (aspartate alpha-decarboxylase); Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.919
ACO45797.1
Putative Branched-chain-amino-acid transaminase (Branched-chain amino acid aminotransferase); Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.912
nadC
Putative Nicotinate-nucleotide diphosphorylase, carboxylating (Nicotinate-nucleotide pyrophosphorylase, carboxylating)(Quinolinate phosphoribosyltransferase, decarboxylating); Belongs to the NadC/ModD family.
     0.693
ACO46947.2
Putative bifunctional protein BirA: biotin operon repressor/biotin--acetyl-CoA-carboxylase ligase.
  
  
 0.659
ACO46816.1
Conserved hypothetical protein.
       0.603
guaA
Putative GMP synthase; Catalyzes the synthesis of GMP from XMP.
     
 0.574
ACO46820.1
Putative Cytochrome-c oxidase (Cytochrome-c oxidase polypeptide I+III, Complex IV); putative membrane protein; Belongs to the heme-copper respiratory oxidase family.
     
 0.555
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
  
 0.539
Your Current Organism:
Deinococcus deserti
NCBI taxonomy Id: 546414
Other names: D. deserti VCD115, Deinococcus deserti VCD115, Deinococcus deserti str. VCD115, Deinococcus deserti strain VCD115
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