STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACO47020.1Putative malate dehydrogenase. (582 aa)    
Predicted Functional Partners:
pyk
Putative Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.954
fumC
Putative fumarate hydratase class II (fumarase); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.952
mdh
Malate dehydrogenase (malic dehydrogenase); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.931
ldh
Putative L-lactate dehydrogenase, precursor (L-lactic acid dehydrogenase); Belongs to the LDH/MDH superfamily.
  
 0.931
ppsA
Putative pyruvate water dikinase (Phosphoenolpyruvate synthase); Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
  
 
 0.928
aceE
Putative Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.923
pdhB
Putative Pyruvate dehydrogenase E1 component subunit beta.
   
 
 0.921
ACO46109.1
Putative Malate synthase; Belongs to the malate synthase family.
  
 
 0.921
ACO46524.1
Putative D-lactate dehydrogenase (cytochrome)(D-lactate ferricytochrome c oxidoreductase)(Lactic acid dehydrogenase).
  
 
 0.914
pdhA
Putative Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
   
 
 0.912
Your Current Organism:
Deinococcus deserti
NCBI taxonomy Id: 546414
Other names: D. deserti VCD115, Deinococcus deserti VCD115, Deinococcus deserti str. VCD115, Deinococcus deserti strain VCD115
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