node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RAD50 | RHM52 | A0A4R8QUS2 | A0A4R8QTH4 | DNA repair protein RAD50. | DNA repair and recombination protein rhm52. | 0.959 |
RAD50 | WRN | A0A4R8QUS2 | A0A4R8RQU6 | DNA repair protein RAD50. | Werner syndrome ATP-dependent helicase. | 0.992 |
RAD50 | dnr-8 | A0A4R8QUS2 | A0A4R8REJ8 | DNA repair protein RAD50. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.952 |
RAD50 | pmt3 | A0A4R8QUS2 | A0A4R8QRS8 | DNA repair protein RAD50. | Ubiquitin-like protein pmt3/smt3. | 0.757 |
RAD50 | rad16 | A0A4R8QUS2 | A0A4R8RG23 | DNA repair protein RAD50. | DNA repair protein rad16. | 0.764 |
RAD50 | rad3 | A0A4R8QUS2 | A0A4R8QC40 | DNA repair protein RAD50. | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.962 |
RAD50 | rhp51 | A0A4R8QUS2 | A0A4R8RI89 | DNA repair protein RAD50. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.923 |
RAD50 | rhp55 | A0A4R8QUS2 | A0A4R8QZJ4 | DNA repair protein RAD50. | DNA repair protein rhp55. | 0.898 |
RAD50 | ssb1 | A0A4R8QUS2 | A0A4R8R0B4 | DNA repair protein RAD50. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.878 |
RAD50 | ssb2 | A0A4R8QUS2 | A0A4R8QT70 | DNA repair protein RAD50. | Replication factor A protein 2. | 0.680 |
RHM52 | RAD50 | A0A4R8QTH4 | A0A4R8QUS2 | DNA repair and recombination protein rhm52. | DNA repair protein RAD50. | 0.959 |
RHM52 | WRN | A0A4R8QTH4 | A0A4R8RQU6 | DNA repair and recombination protein rhm52. | Werner syndrome ATP-dependent helicase. | 0.998 |
RHM52 | dnr-8 | A0A4R8QTH4 | A0A4R8REJ8 | DNA repair and recombination protein rhm52. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.959 |
RHM52 | pmt3 | A0A4R8QTH4 | A0A4R8QRS8 | DNA repair and recombination protein rhm52. | Ubiquitin-like protein pmt3/smt3. | 0.953 |
RHM52 | rad16 | A0A4R8QTH4 | A0A4R8RG23 | DNA repair and recombination protein rhm52. | DNA repair protein rad16. | 0.957 |
RHM52 | rad3 | A0A4R8QTH4 | A0A4R8QC40 | DNA repair and recombination protein rhm52. | Protein kinase rad3; Belongs to the PI3/PI4-kinase family. | 0.959 |
RHM52 | rhp51 | A0A4R8QTH4 | A0A4R8RI89 | DNA repair and recombination protein rhm52. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.994 |
RHM52 | rhp55 | A0A4R8QTH4 | A0A4R8QZJ4 | DNA repair and recombination protein rhm52. | DNA repair protein rhp55. | 0.954 |
RHM52 | ssb1 | A0A4R8QTH4 | A0A4R8R0B4 | DNA repair and recombination protein rhm52. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.996 |
RHM52 | ssb2 | A0A4R8QTH4 | A0A4R8QT70 | DNA repair and recombination protein rhm52. | Replication factor A protein 2. | 0.982 |