STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthDNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (254 aa)    
Predicted Functional Partners:
SDR73108.1
NUDIX domain-containing protein.
    
 0.932
SDT41102.1
Exodeoxyribonuclease-3.
  
 0.915
SDR73085.1
Thiol-disulfide isomerase or thioredoxin.
  
    0.869
SDR76982.1
A/G-specific DNA-adenine glycosylase.
 
 
0.795
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
  
 0.788
SDT43837.1
Deoxyribonuclease-4.
  
 
 0.776
SDR73126.1
Predicted metal-dependent phosphohydrolase, HD superfamily.
       0.773
SDR73135.1
Oligo-1,6-glucosidase.
       0.773
SDR73232.1
Choline dehydrogenase.
       0.746
SDR73239.1
Hypothetical protein.
       0.746
Your Current Organism:
Friedmanniella luteola
NCBI taxonomy Id: 546871
Other names: DSM 21741, F. luteola, Friedmanniella luteola Iwai et al. 2010, Friedmanniella sp. FA1, NBRC 104963, strain FA1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.