STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDU89986.1Aldo/keto reductase family protein. (290 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.696
SDU98130.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
   
 
  0.682
SDU83950.1
L-lactate dehydrogenase complex protein LldF.
   
   0.588
SDU89975.1
DNA-binding transcriptional regulator, ArsR family.
       0.578
SDU89982.1
Cation efflux family protein.
       0.578
SDU92548.1
Uncharacterized protein.
 
    0.570
SDU83418.1
Tat (twin-arginine translocation) pathway signal sequence.
    
   0.562
SDV01547.1
Ferritin-like domain-containing protein.
    
   0.562
SDU89994.1
DNA-binding transcriptional regulator, LacI/PurR family.
       0.551
larC
Hypothetical protein; Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. Belongs to the LarC family.
 
    0.526
Your Current Organism:
Friedmanniella sagamiharensis
NCBI taxonomy Id: 546874
Other names: DSM 21743, F. sagamiharensis, Friedmanniella sagamiharensis Iwai et al. 2010, Friedmanniella sp. FB2, NBRC 104965, strain FB2
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