node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDU86919.1 | SDU90910.1 | SAMN04488544_1218 | SAMN04488544_1810 | DNA ligase D, polymerase domain-containing protein. | Bifunctional non-homologous end joining protein LigD. | 0.679 |
SDU86919.1 | SDU94310.1 | SAMN04488544_1218 | SAMN04488544_2341 | DNA ligase D, polymerase domain-containing protein. | ATP-dependent DNA ligase. | 0.975 |
SDU86919.1 | ku | SAMN04488544_1218 | SAMN04488544_1853 | DNA ligase D, polymerase domain-containing protein. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.842 |
SDU86919.1 | ku-2 | SAMN04488544_1218 | SAMN04488544_3243 | DNA ligase D, polymerase domain-containing protein. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.842 |
SDU88222.1 | SDU90910.1 | SAMN04488544_1400 | SAMN04488544_1810 | 5'-3' exonuclease. | Bifunctional non-homologous end joining protein LigD. | 0.787 |
SDU88222.1 | SDU94310.1 | SAMN04488544_1400 | SAMN04488544_2341 | 5'-3' exonuclease. | ATP-dependent DNA ligase. | 0.849 |
SDU88222.1 | SDV01134.1 | SAMN04488544_1400 | SAMN04488544_3430 | 5'-3' exonuclease. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.987 |
SDU88222.1 | polA | SAMN04488544_1400 | SAMN04488544_2392 | 5'-3' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.697 |
SDU90910.1 | SDU86919.1 | SAMN04488544_1810 | SAMN04488544_1218 | Bifunctional non-homologous end joining protein LigD. | DNA ligase D, polymerase domain-containing protein. | 0.679 |
SDU90910.1 | SDU88222.1 | SAMN04488544_1810 | SAMN04488544_1400 | Bifunctional non-homologous end joining protein LigD. | 5'-3' exonuclease. | 0.787 |
SDU90910.1 | SDU94310.1 | SAMN04488544_1810 | SAMN04488544_2341 | Bifunctional non-homologous end joining protein LigD. | ATP-dependent DNA ligase. | 0.898 |
SDU90910.1 | SDU99228.1 | SAMN04488544_1810 | SAMN04488544_3126 | Bifunctional non-homologous end joining protein LigD. | DNA ligase D. | 0.777 |
SDU90910.1 | SDU99315.1 | SAMN04488544_1810 | SAMN04488544_3139 | Bifunctional non-homologous end joining protein LigD. | DNA ligase D. | 0.696 |
SDU90910.1 | SDV01134.1 | SAMN04488544_1810 | SAMN04488544_3430 | Bifunctional non-homologous end joining protein LigD. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.953 |
SDU90910.1 | ku | SAMN04488544_1810 | SAMN04488544_1853 | Bifunctional non-homologous end joining protein LigD. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.901 |
SDU90910.1 | ku-2 | SAMN04488544_1810 | SAMN04488544_3243 | Bifunctional non-homologous end joining protein LigD. | DNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. | 0.901 |
SDU90910.1 | ligA | SAMN04488544_1810 | SAMN04488544_1574 | Bifunctional non-homologous end joining protein LigD. | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. | 0.801 |
SDU90910.1 | polA | SAMN04488544_1810 | SAMN04488544_2392 | Bifunctional non-homologous end joining protein LigD. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.889 |
SDU94310.1 | SDU86919.1 | SAMN04488544_2341 | SAMN04488544_1218 | ATP-dependent DNA ligase. | DNA ligase D, polymerase domain-containing protein. | 0.975 |
SDU94310.1 | SDU88222.1 | SAMN04488544_2341 | SAMN04488544_1400 | ATP-dependent DNA ligase. | 5'-3' exonuclease. | 0.849 |