STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEF77711.1DNA gyrase/topoisomerase IV, A subunit; KEGG: bth:BT3579 0. topoisomerase IV subunit A K01864; Psort location: Cytoplasmic, score: 8.96. (877 aa)    
Predicted Functional Partners:
EEF74758.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pgi:PG0368 4.4e-209 DNA topoisomerase IV, B subunit, putative K02622; Psort location: Cytoplasmic, score: 8.96.
 
 
 0.958
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
 
 
 0.899
EEF77709.1
Peptidase, S41 family; KEGG: ccr:CC2028 9.8e-11 carboxyl-terminal processing protease K03797; Psort location: Cytoplasmic, score: 8.96.
       0.823
EEF77710.1
Hypothetical protein.
       0.823
glyS
glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family.
 
    0.597
argS
arginine--tRNA ligase; KEGG: bth:BT2829 2.4e-281 arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.26.
 
  
 0.577
EEF77712.1
MATE efflux family protein; Psort location: CytoplasmicMembrane, score: 10.00.
     
 0.571
secD
Export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily.
 
  
 0.560
EEF77715.1
KEGG: vpa:VP2778 2.8e-17 peptidyl-prolyl cis-trans isomerase, FKBP-type K03772; Psort location: Periplasmic, score: 9.44.
  
  
 0.536
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
  
 0.509
Your Current Organism:
Bacteroides coprophilus
NCBI taxonomy Id: 547042
Other names: B. coprophilus DSM 18228 = JCM 13818, Bacteroides coprophilus CB42, Bacteroides coprophilus DSM 18228, Bacteroides coprophilus DSM 18228 = JCM 13818, Bacteroides coprophilus JCM 13818, Bacteroides coprophilus JCM 13818 = DSM 18228
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