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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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AGG14537.1IMG reference gene:2506377088; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; biotin protein ligase domain protein; SPTR: Biotin/acetyl-CoA-carboxylase ligase; KEGG: tal:Thal_0265 biotin/acetyl-CoA-carboxylase ligase; COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR003142:IPR004408. (237 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.939
AGG14536.1
Putative CheA signal transduction histidine kinase; IMG reference gene:2506377087; PFAM: Hpt domain; PFAM: Hpt domain protein; SPTR: Putative CheA signal transduction histidine kinase; KEGG: sul:SYO3AOP1_0926 CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207.
       0.786
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.702
AGG14532.1
Putative transcriptional acitvator, Baf family; IMG reference gene:2506377083; PFAM: Type III pantothenate kinase; TIGRFAM: pantothenate kinase, type III; TIGRFAM: transcriptional activator, Baf family; PFAM: Bvg accessory factor; SPTR: Putative transcriptional acitvator, Baf family; KEGG: hth:HTH_1472 putative transcriptional acitvator; COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619.
 
    0.691
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
       0.690
AGG14538.1
Periplasmic chaperone for outer membrane proteins Skp; IMG reference gene:2506377089; PFAM: Outer membrane protein (OmpH-like); PFAM: outer membrane chaperone Skp (OmpH); SPTR: Outer membrane chaperone Skp (OmpH); KEGG: tal:Thal_0578 outer membrane chaperone Skp (OmpH); InterPro IPR005632.
       0.686
AGG15308.1
CMP/dCMP deaminase zinc-binding protein; IMG reference gene:2506377904; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: CMP/dCMP deaminase zinc-binding; KEGG: aae:aq_903 hypothetical protein; COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR016192:IPR002125.
  
    0.683
AGG15671.1
acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2506378284; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: hth:HTH_1917 biotin carboxylase; COGs: [...]
 
  
 0.635
AGG15724.1
acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2506378340; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: saf:SULAZ_0524 acetyl-CoA carboxylase, [...]
 
  
 0.633
AGG15097.1
acetyl-CoA carboxylase, biotin carboxylase; IMG reference gene:2506377680; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: Acetyl-CoA carboxylase, biotin carboxylase; KEGG: aae:aq_1470 biotin carboxylase; COGs: [...]
 
  
 0.628
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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