STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mnmAtRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (342 aa)    
Predicted Functional Partners:
AGG14722.1
Queuosine synthesis; IMG reference gene:2506377279; PFAM: Thiamine biosynthesis protein (ThiI); PFAM: Queuosine synthesis-like; SPTR: Thiamine biosynthesis protein; KEGG: hth:HTH_1302 thiamine biosynthesis protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR018317.
     
  0.900
AGG14684.1
Protein of unknown function DUF140; IMG reference gene:2506377241; PFAM: Permease; TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF140; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_0213 ABC transporter permease protein; COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453.
       0.779
AGG14685.1
Rsbr family protein; IMG reference gene:2506377242; PFAM: Rsbr N terminal; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_0170 hypothetical protein.
       0.779
AGG14683.1
Thioredoxin; IMG reference gene:2506377240; PFAM: Thioredoxin-like; SMART: UAS; SPTR: Putative uncharacterized protein; KEGG: aae:aq_1811 thioredoxin; InterPro IPR017936:IPR006577.
       0.773
AGG14723.1
IMG reference gene:2506377280; PFAM: NifU-like N terminal domain; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU domain protein; KEGG: tal:Thal_0980 nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871.
 
  
 0.748
AGG14681.1
Tetratricopeptide TPR_1 repeat-containing protein; IMG reference gene:2506377238; PFAM: TPR repeat; Tetratricopeptide repeat; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; KEGG: tal:Thal_0816 TPR repeat-containing protein; InterPro IPR019734:IPR013026:IPR001440.
    
  0.718
AGG14680.1
IMG reference gene:2506377237; PFAM: Protein of unknown function (DUF503); PFAM: protein of unknown function DUF503; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_0587 hypothetical protein; COGs: COG1550 conserved hypothetical protein; InterPro IPR007546.
       0.670
mnmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
 
 0.592
pheT
phenylalanyl-tRNA synthetase beta subunit; IMG reference gene:2506377779; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; KEGG: aae:aq_1730 phenylalanyl-tRNA synthetase subunit beta; COGs: COG0072 Phenylalanyl-tRNA sy [...]
  
  
 0.581
AGG14686.1
DMT(drug/metabolite transporter) superfamily permease; IMG reference gene:2506377243; PFAM: EamA-like transporter family; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; KEGG: protein of unknown function DUF6 transmembrane; InterPro IPR000620.
       0.579
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
Server load: low (14%) [HD]
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