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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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bioAAdenosylmethionine--8-amino-7-oxononanoatetransa minase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. (444 aa)    
Predicted Functional Partners:
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.998
AGG14857.1
8-amino-7-oxononanoate synthase; IMG reference gene:2506377421; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; PRIAM: 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; SPTR: 8-amino-7-oxononanoate synthase; KEGG: aae:aq_626 8-amino-7-oxononanoate synthase; COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR001917:IPR004839.
 
 
 0.990
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 0.988
fumC
Fumarase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
       0.781
AGG14816.1
Protein of unknown function DUF55; IMG reference gene:2506377379; PFAM: EVE domain; PFAM: protein of unknown function DUF55; SPTR: Putative uncharacterized protein; KEGG: sul:SYO3AOP1_0170 protein of unknown function DUF55; COGs: COG2947 conserved hypothetical protein; InterPro IPR002740.
       0.775
AGG14817.1
Putative membrane protein; IMG reference gene:2506377380; PFAM: Protein of unknown function (DUF996); SPTR: Putative uncharacterized protein; KEGG: mja:MJ1644 hypothetical protein; COGs: COG2245 membrane protein; InterPro IPR000276.
       0.773
AGG15129.1
6-carboxyhexanoate-CoA ligase; IMG reference gene:2506377713; PFAM: 6-carboxyhexanoate--CoA ligase; TIGRFAM: 6-carboxyhexanoate--CoA ligase; TIGRFAM: 6-carboxyhexanoate/CoA ligase; PRIAM: 6-carboxyhexanoate--CoA ligase; PFAM: 6-carboxyhexanoate--CoA ligase; SPTR: 6-carboxyhexanoate/CoA ligase; KEGG: aae:aq_1659 6-carboxyhexanoate--CoA ligase; COGs: COG1424 Pimeloyl-CoA synthetase; InterPro IPR005499.
 
  
 0.754
def
Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
     
 0.522
pheT
phenylalanyl-tRNA synthetase beta subunit; IMG reference gene:2506377779; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding domain; B3/4 domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain-containing protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; KEGG: aae:aq_1730 phenylalanyl-tRNA synthetase subunit beta; COGs: COG0072 Phenylalanyl-tRNA sy [...]
     
 0.501
AGG15186.1
IMG reference gene:2506377777; PFAM: FlaG protein; PFAM: flagellar protein FlaG protein; SPTR: Flagellar protein FlaG protein; KEGG: pmx:PERMA_1619 flagellar protein FlaG; COGs: COG1334 Uncharacterized flagellar protein FlaG; InterPro IPR005186.
    
   0.499
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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