STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGG14995.1CRISPR-associated protein Cas5; IMG reference gene:2506377567; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, N-terminal domain; SPTR: CRISPR-associated protein Cas5; TIGRFAM: CRISPR-associated protein Cas5; KEGG: tal:Thal_0014 CRISPR-associated protein Cas5 family; InterPro IPR013422. (223 aa)    
Predicted Functional Partners:
AGG14994.1
CRISPR-associated autoregulator, Cst2 family; IMG reference gene:2506377566; PFAM: CRISPR-associated negative auto-regulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP; TIGRFAM: CRISPR-associated autoregulator DevR family; SPTR: CRISPR-associated autoregulator DevR family; KEGG: lba:Lebu_0798 CRISPR-associated autoregulator, DevR family; InterPro IPR010154.
 
 
 0.974
AGG14996.1
CRISPR-associated helicase Cas3; IMG reference gene:2506377568; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3; KEGG: pmx:PERMA_1338 crispr-associated helicase Cas3; COGs: COG1203 helicase; InterProIPR006483:IPR006474:IPR014001:IPR001650:IPR 014021.
 
 
 0.972
AGG14992.1
CRISPR-associated protein Cas6; IMG reference gene:2506377564; PFAM: CRISPR associated protein Cas6; TIGRFAM: CRISPR-associated endoribonuclease Cas6; TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; SPTR: CRISPR-associated protein Cas6; KEGG: saf:SULAZ_0823 crispr-associated protein Cas6; COGs: COG1583 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010156:IPR002743.
 
   
 0.932
AGG15484.1
CRISPR-associated autoregulator, Cst2 family; IMG reference gene:2506378085; PFAM: CRISPR-associated negative auto-regulator DevR/Csa2; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP; TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, DevR family; SPTR: CRISPR-associated autoregulator, DevR family; KEGG: tal:Thal_0013 CRISPR-associated autoregulator, DevR family; COGs: COG1857 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR010154:IPR013414.
 
 
 0.889
AGG15486.1
CRISPR-associated helicase, Cas3 family; IMG reference gene:2506378087; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: CRISPR-associated helicase Cas3; KEGG: aae:aq_371 hypothetical protein; COGs: COG1203 helicase; InterProIPR014021:IPR001650:IPR011545:IPR014001:IPR 006483:IPR006474.
 
 
 0.884
AGG15487.1
CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.770
AGG14735.1
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
   
 0.751
cas1-2
CRISPR-associated protein, Cas1 family; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.723
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
   
 0.694
AGG14993.1
Hypothetical protein; IMG reference gene:2506377565; SPTR: Putative uncharacterized protein; KEGG: sul:SYO3AOP1_0668 CRISPR-associated CXXC_CXXC protein Cst1.
       0.648
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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