STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Cooccurrence
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[Homology]
Score
AGG15124.1IMG reference gene:2506377708; PFAM: Bacterial DNA-binding protein; PFAM: histone family protein DNA-binding protein; COGs: COG0776 Bacterial nucleoid DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: Histone family protein DNA-binding protein; KEGG: aae:aq_2174 integration host factor beta subunit; InterPro IPR000119; Belongs to the bacterial histone-like protein family. (99 aa)    
Predicted Functional Partners:
AGG15123.1
Geranylgeranyl reductase; IMG reference gene:2506377707; PFAM: FAD binding domain; TIGRFAM: geranylgeranyl reductase family; TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; SPTR: Geranylgeranyl reductase; KEGG: hth:HTH_1747 geranylgeranyl reductase; COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR011777:IPR003042:IPR002938.
       0.816
AGG15121.1
Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity.
     
 0.784
yajC
Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.
  
  
 0.777
AGG14472.1
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.767
AGG15120.1
Histidine kinase; IMG reference gene:2506377704; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phospho-acceptor) domain; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; KEGG: hth:HTH_1082 sensor histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467.
     
 0.762
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
 0.761
AGG15745.1
UvrD/REP helicase; IMG reference gene:2506378363; PFAM: UvrD-like helicase C-terminal domain; UvrD/REP helicase N-terminal domain; PFAM: UvrD/REP helicase; SPTR: UvrD/REP helicase; KEGG: aae:aq_793 ATP-dependent DNA helicase REP; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016:IPR014017:IPR000212.
     
 0.753
AGG15912.1
Replication restart DNA helicase PriA; IMG reference gene:2506378542; SPTR: Primosomal protein N' (Replication factor Y)-superfamily II helicase-like protein; KEGG: hth:HTH_1037 primosomal protein N'; COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase.
    
  0.742
gmhA
Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily.
     
  0.721
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
       0.714
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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