STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGG15236.1Metallo-beta-lactamase family protein; IMG reference gene:2506377828; PFAM: Beta-lactamase superfamily domain; manually curated; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1889 metallo-beta-lactamase family protein. (251 aa)    
Predicted Functional Partners:
AGG15235.1
IMG reference gene:2506377827; SPTR: Putative uncharacterized protein; KEGG: rci:RCIX1468 putative polysaccharide biosynthesis protein.
       0.773
AGG15232.1
IMG reference gene:2506377824; PFAM: Polysaccharide deacetylase; PFAM: polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; KEGG: saf:SULAZ_0979 polysaccharide deacetylase family protein; COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509.
  
    0.770
AGG15233.1
Putative permease; IMG reference gene:2506377825; PFAM: Sulfite exporter TauE/SafE; PFAM: protein of unknown function DUF81; SPTR: Putative uncharacterized protein; KEGG: tpd:Teth39_0912 hypothetical protein; InterPro IPR002781.
       0.768
AGG15234.1
Hypothetical protein; IMG reference gene:2506377826; PFAM: Amino acid permease; SPTR: Amino acid transporter-like protein; KEGG: tex:Teth514_1974 amino acid transporter-like protein; COGs: COG0531 Amino acid transporter.
       0.762
AGG15237.1
4Fe-4S ferredoxin; IMG reference gene:2506377829; PFAM: 4Fe-4S single cluster domain; SPTR: Ferredoxin; KEGG: hth:HTH_1891 4Fe-4S ferredoxin.
       0.717
AGG15731.1
Polynucleotide adenylyltransferase region; IMG reference gene:2506378347; PFAM: DHH family; CBS domain; Poly A polymerase head domain; Probable RNA and SrmB- binding site of polymerase A; PFAM: Polynucleotide adenylyltransferase region; CBS domain containing protein; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; SPTR: Polynucleotide adenylyltransferase region; KEGG: aae:aq_411 poly A polymerase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR000644:IPR001667:IPR002646; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase [...]
  
  
 0.585
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.580
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.549
AGG15248.1
Putative kinase; IMG reference gene:2506377840; PFAM: AAA domain; SPTR: Putative uncharacterized protein; KEGG: aae:aq_1484 hypothetical protein; COGs: COG0645 kinase.
 
     0.488
AGG15542.1
Hydrolase, TatD family; IMG reference gene:2506378144; PFAM: Radical SAM superfamily; 4Fe-4S single cluster domain; TatD related DNase; TIGRFAM: hydrolase, TatD family; radical SAM protein, TatD family-associated; TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; Radical SAM domain protein; SPTR: Hydrolase, TatD family; KEGG: hth:HTH_0942 deoxyribonuclease, TatD family; COGs: COG0084 Mg-dependent DNase; InterPro IPR018228:IPR001130:IPR007197:IPR015991.
     
 0.461
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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