| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGG14914.1 | AGG15381.1 | HydHO_0584 | HydHO_1066 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | 0.980 |
| AGG14914.1 | AGG15384.1 | HydHO_0584 | HydHO_1069 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | DsrE family protein; IMG reference gene:2506377983; PFAM: DsrE/DsrF-like family; PFAM: DsrE family protein; SPTR: DsrE family protein; KEGG: hth:HTH_1875 hypothetical protein; COGs: COG2044 peroxiredoxins; InterPro IPR003787. | 0.781 |
| AGG14914.1 | AGG15386.1 | HydHO_0584 | HydHO_1071 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Glycine cleavage H-protein; IMG reference gene:2506377985; PFAM: Glycine cleavage H-protein; PFAM: glycine cleavage H-protein; SPTR: Glycine cleavage H-protein; KEGG: tal:Thal_1342 glycine cleavage H-protein; COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR003016:IPR002930. | 0.478 |
| AGG14914.1 | AGG15387.1 | HydHO_0584 | HydHO_1072 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | CoB--CoM heterodisulfide reductase; IMG reference gene:2506377986; PFAM: Cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: CoB--CoM heterodisulfide reductase; KEGG: hth:HTH_1878 heterodisulfide reductase subunit B; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017. | 0.696 |
| AGG14914.1 | AGG15388.1 | HydHO_0584 | HydHO_1073 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Heterodisulfide reductase subunit C; IMG reference gene:2506377987; PFAM: 4Fe-4S dicluster domain; SPTR: Heterodisulfide reductase subunit C; KEGG: hth:HTH_1879 heterodisulfide reductase subunit C; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017896. | 0.767 |
| AGG14914.1 | AGG15389.1 | HydHO_0584 | HydHO_1074 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Hypothetical protein; IMG reference gene:2506377988; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1880 hypothetical protein. | 0.787 |
| AGG14914.1 | AGG15390.1 | HydHO_0584 | HydHO_1075 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | IMG reference gene:2506377989; PFAM: Pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: hth:HTH_1881 heterodisulfide reductase subunit A; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR013027. | 0.799 |
| AGG14914.1 | AGG15391.1 | HydHO_0584 | HydHO_1076 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Heterodisulfide reductase, subunit B; IMG reference gene:2506377990; PFAM: Cysteine-rich domain; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1882 heterodisulfide reductase subunit B; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017. | 0.773 |
| AGG14914.1 | AGG15392.1 | HydHO_0584 | HydHO_1077 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Heterodisulfide reductase subunit C; IMG reference gene:2506377991; PFAM: 4Fe-4S dicluster domain; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1883 heterodisulfide reductase subunit C; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017896. | 0.775 |
| AGG14914.1 | AGG15393.1 | HydHO_0584 | HydHO_1078 | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | Peroxiredoxins-like protein; IMG reference gene:2506377992; PFAM: DsrE/DsrF-like family; manually curated; SPTR: Putative uncharacterized protein; KEGG: tal:Thal_1349 peroxiredoxins-like protein; COGs: COG2044 peroxiredoxins. | 0.779 |
| AGG15381.1 | AGG14914.1 | HydHO_1066 | HydHO_0584 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | IMG reference gene:2506377479; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: hth:HTH_1871 biotin synthase-related protein; COGs: COG2516 Biotin synthase-related protein; InterPro IPR006638:IPR007197. | 0.980 |
| AGG15381.1 | AGG15384.1 | HydHO_1066 | HydHO_1069 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | DsrE family protein; IMG reference gene:2506377983; PFAM: DsrE/DsrF-like family; PFAM: DsrE family protein; SPTR: DsrE family protein; KEGG: hth:HTH_1875 hypothetical protein; COGs: COG2044 peroxiredoxins; InterPro IPR003787. | 0.873 |
| AGG15381.1 | AGG15386.1 | HydHO_1066 | HydHO_1071 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Glycine cleavage H-protein; IMG reference gene:2506377985; PFAM: Glycine cleavage H-protein; PFAM: glycine cleavage H-protein; SPTR: Glycine cleavage H-protein; KEGG: tal:Thal_1342 glycine cleavage H-protein; COGs: COG0509 Glycine cleavage system H protein (lipoate-binding); InterPro IPR003016:IPR002930. | 0.733 |
| AGG15381.1 | AGG15387.1 | HydHO_1066 | HydHO_1072 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | CoB--CoM heterodisulfide reductase; IMG reference gene:2506377986; PFAM: Cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: CoB--CoM heterodisulfide reductase; KEGG: hth:HTH_1878 heterodisulfide reductase subunit B; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017. | 0.786 |
| AGG15381.1 | AGG15388.1 | HydHO_1066 | HydHO_1073 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Heterodisulfide reductase subunit C; IMG reference gene:2506377987; PFAM: 4Fe-4S dicluster domain; SPTR: Heterodisulfide reductase subunit C; KEGG: hth:HTH_1879 heterodisulfide reductase subunit C; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017896. | 0.842 |
| AGG15381.1 | AGG15389.1 | HydHO_1066 | HydHO_1074 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Hypothetical protein; IMG reference gene:2506377988; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1880 hypothetical protein. | 0.855 |
| AGG15381.1 | AGG15390.1 | HydHO_1066 | HydHO_1075 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | IMG reference gene:2506377989; PFAM: Pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; KEGG: hth:HTH_1881 heterodisulfide reductase subunit A; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR013027. | 0.855 |
| AGG15381.1 | AGG15391.1 | HydHO_1066 | HydHO_1076 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Heterodisulfide reductase, subunit B; IMG reference gene:2506377990; PFAM: Cysteine-rich domain; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1882 heterodisulfide reductase subunit B; COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017. | 0.844 |
| AGG15381.1 | AGG15392.1 | HydHO_1066 | HydHO_1077 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Heterodisulfide reductase subunit C; IMG reference gene:2506377991; PFAM: 4Fe-4S dicluster domain; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_1883 heterodisulfide reductase subunit C; COGs: COG1150 Heterodisulfide reductase subunit C; InterPro IPR017900:IPR017896. | 0.832 |
| AGG15381.1 | AGG15393.1 | HydHO_1066 | HydHO_1078 | IMG reference gene:2506377980; PFAM: Radical SAM superfamily; PFAM: Radical SAM domain protein; COGs: COG1856 Uncharacterized homolog of biotin synthetase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; KEGG: aae:aq_403 hypothetical protein; InterPro IPR007197:IPR006638. | Peroxiredoxins-like protein; IMG reference gene:2506377992; PFAM: DsrE/DsrF-like family; manually curated; SPTR: Putative uncharacterized protein; KEGG: tal:Thal_1349 peroxiredoxins-like protein; COGs: COG2044 peroxiredoxins. | 0.825 |