STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
gmhAPhosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. (197 aa)    
Predicted Functional Partners:
gmhC
PfkB domain protein GmhC; IMG reference gene:2506377689; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I; PFAM: PfkB domain protein; SPTR: PfkB domain protein; KEGG: hth:HTH_0439 ADP-heptose synthase; COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR002173:IPR011611.
  
 0.985
AGG15864.1
rfaE bifunctional protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
   
 0.953
AGG15664.1
ComEC/Rec2-related protein; IMG reference gene:2506378277; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; KEGG: aae:aq_1618 hypothetical protein; InterPro IPR004477.
       0.784
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.691
AGG15377.1
IMG reference gene:2506377976; PFAM: Glycosyltransferase family 9 (heptosyltransferase); PFAM: glycosyl transferase family 9; SPTR: Glycosyl transferase family 9; KEGG: aae:aq_145 ADP-heptose:LPS heptosyltransferase; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201.
 
   
 0.627
AGG15661.1
HAD-superfamily hydrolase, subfamily IA, variant 1; IMG reference gene:2506378274; PFAM: Haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; 2-phosphoglycolate phosphatase, prokaryotic; PFAM: Haloacid dehalogenase domain protein hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; KEGG: aae:aq_1342 phosphoglycolate phosphatase; COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439.
  
    0.582
AGG14508.1
KpsF/GutQ family protein; IMG reference gene:2506377059; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PRIAM: Arabinose-5-phosphate isomerase; PFAM: sugar isomerase (SIS); CBS domain containing protein; SMART: CBS domain containing protein; SPTR: KpsF/GutQ family protein; KEGG: tal:Thal_0361 KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR000644:IPR004800; Belongs to the SIS family. GutQ/KpsF subfamily.
     
 0.580
AGG15662.1
N6-adenine-specific methylase; IMG reference gene:2506378275; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; manually curated; PFAM: Conserved hypothetical protein CHP00095; SPTR: Putative uncharacterized protein; KEGG: hth:HTH_0683 putative methyltransferase; COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398:IPR002052.
       0.567
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.490
AGG14988.1
IMG reference gene:2506377557; PFAM: Glycosyltransferase family 9 (heptosyltransferase); PFAM: glycosyl transferase family 9; SPTR: Glycosyl transferase family 9; KEGG: aae:aq_1543 ADP-heptose:LPS heptosyltransferase; COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201.
 
   
 0.471
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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