STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGG15768.1Phage SPO1 DNA polymerase-related protein; IMG reference gene:2506378389; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Phage SPO1 DNA polymerase-related protein; KEGG: hth:HTH_0122 phage SPO1 DNA polymerase-related protein; COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122:IPR005273. (249 aa)    
Predicted Functional Partners:
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate.
     
 0.791
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
       0.779
AGG15766.1
IMG reference gene:2506378387; PFAM: SRP54-type protein, GTPase domain; PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; SPTR: GTP-binding signal recognition particle SRP54 G-domain protein; KEGG: tal:Thal_1167 flagellar biosynthetic protein FlhF; COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR000897:IPR003593.
       0.779
AGG15767.1
Cobyrinic acid ac-diamide synthase; IMG reference gene:2506378388; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; SPTR: Cobyrinic acid ac-diamide synthase; KEGG: tal:Thal_1166 cobyrinic acid ac-diamide synthase; COGs: COG0455 ATPase involved in chromosome partitioning.
       0.779
AGG15764.1
Hypothetical protein; IMG reference gene:2506378385; SPTR: Putative uncharacterized protein; KEGG: cdf:CD1520 hypothetical protein.
       0.773
AGG14775.1
IMG reference gene:2506377336; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; KEGG: hth:HTH_0374 single-stranded DNA-binding protein; COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424.
  
 
   0.743
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
       0.691
AGG15761.1
IMG reference gene:2506378382; PFAM: 4Fe-4S dicluster domain; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: tal:Thal_0697 4Fe-4S ferredoxin iron-sulfur binding domain protein; COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterPro IPR017900:IPR017896.
       0.690
AGG15744.1
IMG reference gene:2506378362; PFAM: Glycoprotease family; SPTR: Metal-dependent protease putative molecular chaperone-like protein; KEGG: aae:aq_082 hypothetical protein; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone.
  
    0.581
AGG14514.1
Flagellar basal-body rod protein FlgC; IMG reference gene:2506377065; PFAM: Flagellar basal body rod FlgEFG protein C-terminal; Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; SPTR: Flagellar basal-body rod protein FlgC; KEGG: aae:aq_1183 flagellar biosynthesis FlgC; COGs: COG1558 Flagellar basal body rod protein; InterPro IPR019776:IPR001444:IPR010930:IPR006299.
    
   0.562
Your Current Organism:
Hydrogenobaculum sp. HO
NCBI taxonomy Id: 547144
Other names: H. sp. HO
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