STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egtDL-histidine N(alpha)-methyltransferase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family. (321 aa)    
Predicted Functional Partners:
OSC26657.1
iron(II)-dependent oxidoreductase EgtB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
OSC26658.1
Ergothioneine biosynthesis protein EgtC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.995
OSC26656.1
Ergothioneine biosynthesis glutamate--cysteine ligase EgtA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.986
OSC26660.1
Ergothioneine biosynthesis PLP-dependent enzyme EgtE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.984
OSC29699.1
DUF58 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.925
OSC26667.1
DUF58 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.925
purD
Phosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family.
      
 0.923
OSC25643.1
Sulfatase-modifying factor 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.901
OSC22010.1
DUF58 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.860
OSC22286.1
CoA ester lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.823
Your Current Organism:
Mycobacterium vulneris
NCBI taxonomy Id: 547163
Other names: CIP 109859, DSM 45247, JCM 18115, M. vulneris, Mycobacterium sp. ACS3670, Mycobacterium sp. ACS4093, Mycobacterium sp. ACS5020, Mycobacterium sp. ICS2043, Mycobacterium sp. NLA000700772, Mycobacterium sp. NLA009601918, Mycobacterium vulneris van Ingen et al. 2009, Mycolicibacterium vulneris, Mycolicibacterium vulneris (van Ingen et al. 2009) Gupta et al. 2018, strain NLA000700772
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