STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
Experiments
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[Homology]
Score
Mmah_0369COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: mmb:Mmol_0499 two component transcriptional regulator PhoB, winged helix family; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Q12U26 Response regulator receiver; PFAM: Response regulator receiver domain. (355 aa)    
Predicted Functional Partners:
Mmah_0428
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 013656:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: pmy:Pmen_0835 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q8TPF6 Sensor protein; TIGR [...]
 
 0.970
Mmah_0609
COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013656:IPR003594:IPR003661:IPR 000014:IPR000700:IPR001789:IPR005467; KEGG: ppd:Ppro_2725 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12TG1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATP [...]
 
 0.939
Mmah_0821
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR003661:IPR005467; KEGG: dma:DMR_09640 putative sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12Y17 Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 0.936
Mmah_1250
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR013767:IPR013656:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Q12U10 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA [...]
 
 
 0.930
Mmah_0912
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013767:IPR 003594:IPR003661:IPR000014:IPR000700:IPR005467; KEGG: gem:GM21_1199 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS domain containing protein; SPTR: Q8TNJ1 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; Histidine kinase [...]
 
 0.929
Mmah_1558
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR013655:IPR003018:IPR013656:IPR 013767:IPR003594:IPR003661:IPR001610:IPR000014:IPR000700:I PR005467; KEGG: dal:Dalk_5102 putative PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Q12ZM3 [...]
 
 0.927
Mmah_0908
COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR013767:IPR003594:IPR000014:IPR 000700:IPR005467; KEGG: nmu:Nmul_A1289 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Q2Y4W7 Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 0.926
Mmah_0019
Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003594:IPR005467; KEGG: afw:Anae109_3161 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Q12XC6 ATP-binding region, ATPase-like protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase.
 
 
 0.913
Mmah_1063
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR004010:IPR003594:IPR003660:IPR 003661:IPR005467; KEGG: dal:Dalk_1747 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; Cache domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PRIAM: Histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Q12YI4 Sensor protein; PFAM: Cache domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
   
 0.789
Mmah_0974
Putative PAS/PAC sensor protein; InterProIPR013655:IPR013767:IPR001610:IPR000014:IPR 000700; KEGG: pca:Pcar_0299 two component sensor histidine kinase; PFAM: PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein; SPTR: Q12XR0 Multi-PAS sensor; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.788
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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