STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mmah_0559COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR000878:IPR003043:IPR006366; KEGG: sfu:Sfum_3201 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Q8Q031 Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (254 aa)    
Predicted Functional Partners:
Mmah_0558
COGs: COG1587 Uroporphyrinogen-III synthase; InterPro IPR003754; KEGG: dal:Dalk_4009 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrinogen III synthase HEM4; SPTR: Q12WZ2 Uroporphyrinogen-III synthase; PFAM: Uroporphyrinogen-III synthase HemD.
 
 0.999
Mmah_1457
COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367; KEGG: prw:PsycPRwf_1107 uroporphyrin-III C-methyltransferase; PRIAM: Sirohydrochlorin ferrochelatase; SPTR: Q46CH4 Precorrin-2 oxidase / ferrochelatase; TIGRFAM: siroheme synthase; TIGRFAM: siroheme synthase, N-terminal domain.
 
 0.999
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 0.982
Mmah_1497
Cobalt-factor II C20-methyltransferase; COGs: COG2243 Precorrin-2 methylase; InterPro IPR000878:IPR003043; KEGG: dde:Dde_3107 cobalt-factor II C20-methyltransferase.
 
 
 0.942
Mmah_0020
COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: ppd:Ppro_1430 uroporphyrinogen decarboxylase; PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Q12XC7 Uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family.
    
 0.914
Mmah_0657
COGs: COG0407 Uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: geo:Geob_2498 uroporphyrinogen decarboxylase (URO-D); PFAM: Uroporphyrinogen decarboxylase (URO-D); SPTR: Q8TSF1 Methyltransferase; PFAM: Uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family.
    
 0.914
Mmah_0161
COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterProIPR001450:IPR002478:IPR002500:IPR017900:IPR 004521; KEGG: gem:GM21_0790 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; PUA domain containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SMART: PUA domain containing protein; SPTR: Q12UR6 Phosphoadenosine phosphosulfate reductase; PFAM: PUA domain; Phosphoadenosine phosphosulfate reductase family; TIGRFAM: uncharacterized domain 2.
 
  
 0.841
Mmah_0557
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dol:Dole_1225 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Q46BK8 Metallo cofactor biosynthesis protein; PFAM: Radical SAM superfamily.
  
  
 0.834
Mmah_1459
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: dps:DP2824 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Q12WM6 Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
  
 0.823
Mmah_1632
COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: gem:GM21_0790 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: Q12WD1 Phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulfate reductase family.
  
  
 0.814
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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