STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
Mmah_0697SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: wsu:WS1004 hypothetical protein; PFAM: SirA family protein; SPTR: O29697 UPF0033 protein AF_0554; PFAM: SirA-like protein. (81 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.973
Mmah_0896
COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192; KEGG: scl:sce7329 cysteine desulfurase; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Q8TSI8 Homocysteine desulfhydrase; PFAM: Aminotransferase class-V.
   
 0.973
Mmah_0898
SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: mfa:Mfla_0093 SirA-like protein; PFAM: SirA family protein; SPTR: Q12ZL8 SirA-like protein; PFAM: SirA-like protein.
  
  
  0.921
Mmah_0710
SirA family protein; COGs: COG0425 redox protein regulator of disulfide bond formation; InterPro IPR001455; KEGG: tbd:Tbd_1982 hypothetical protein; PFAM: SirA family protein; SPTR: B8GJE1 SirA family protein; PFAM: SirA-like protein.
  
  
  0.913
Mmah_0895
Nitrogen-fixing NifU domain protein; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871; KEGG: dia:Dtpsy_1639 FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; SPTR: Q8TSI9 NifU family protein; PFAM: NifU-like N terminal domain; Domain of unknown function DUF59.
     
 0.601
Mmah_0161
COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterProIPR001450:IPR002478:IPR002500:IPR017900:IPR 004521; KEGG: gem:GM21_0790 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; PUA domain containing protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SMART: PUA domain containing protein; SPTR: Q12UR6 Phosphoadenosine phosphosulfate reductase; PFAM: PUA domain; Phosphoadenosine phosphosulfate reductase family; TIGRFAM: uncharacterized domain 2.
  
  
 0.590
Mmah_1632
COGs: COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase; InterPro IPR002500; KEGG: gem:GM21_0790 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: Q12WD1 Phosphoadenosine phosphosulfate reductase; PFAM: Phosphoadenosine phosphosulfate reductase family.
  
  
 0.590
Mmah_0694
Mov34/MPN/PAD-1 family protein; COGs: COG1310 metal-dependent protease of the PAD1/JAB1 superfamily; InterPro IPR000555; KEGG: wsu:WS1005 hypothetical protein; PFAM: Mov34/MPN/PAD-1 family protein; SMART: Mov34/MPN/PAD-1 family protein; SPTR: Q0W197 Predicted protease (Mov34 family); PFAM: Mov34/MPN/PAD-1 family.
 
     0.580
Mmah_0105
Conserved repeat domain protein; InterPro IPR002931:IPR016160:IPR001434; KEGG: geo:Geob_3466 transglutaminase domain protein; PFAM: transglutaminase domain protein; SMART: transglutaminase domain protein; SPTR: B6KF59 Putative uncharacterized protein; TIGRFAM: conserved repeat domain protein; PFAM: Transglutaminase-like superfamily; TIGRFAM: conserved repeat domain.
     
 0.551
Mmah_0709
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR007901:IPR000594; KEGG: gme:Gmet_1568 UBA/ThiF-type NAD/FAD binding fold:MoeZ/MoeB; PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; SPTR: Q12ZH9 UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
   
 0.489
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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