STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mmah_1386Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: mxa:MXAN_3043 cation efflux family protein; PFAM: cation efflux protein; SPTR: Q12X76 Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter. (293 aa)    
Predicted Functional Partners:
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.716
Mmah_1107
COGs: COG0039 Malate/lactate dehydrogenase; InterPro IPR001557:IPR001236:IPR011275; KEGG: dol:Dole_2374 malate dehydrogenase, NAD-dependent; PFAM: Lactate/malate dehydrogenase; PRIAM: Malate dehydrogenase; SPTR: Q8PVJ7 Malate dehydrogenase; TIGRFAM: malate dehydrogenase, NAD-dependent; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent; Belongs to the LDH/MDH superfamily.
  
    0.631
Mmah_1385
Cobyrinic acid ac-diamide synthase; COGs: COG3640 CO dehydrogenase maturation factor; InterPro IPR002586; KEGG: sfu:Sfum_4099 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; SPTR: Q12X77 Cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
       0.587
Mmah_0623
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR003142:IPR013196:IPR004143:IPR004408; KEGG: gur:Gura_2817 biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; Helix-turn-helix type 11 domain protein; biotin protein ligase domain protein; SPTR: Q8PVX6 Biotin--[acetyl-COA-carboxylase] synthetase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain.
  
  
 0.544
Mmah_1674
Sodium/proton antiporter, CPA1 family (TC 2.A.36); COGs: COG0025 NhaP-type Na+/H+ and K+/H+ antiporter; InterPro IPR006036:IPR006037:IPR003148:IPR006153; KEGG: dol:Dole_2292 sodium/hydrogen exchanger; PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; SPTR: Q12W95 Sodium/hydrogen exchanger; PFAM: TrkA-N domain; Sodium/hydrogen exchanger family; TrkA-C domain.
 
   
 0.433
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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