STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIL1Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity) (414 aa)    
Predicted Functional Partners:
LHS1
annotation not available
   
 0.984
KAR2
annotation not available
   
 
 0.961
AHA1
annotation not available
   
  
 0.943
HSP90
Heat shock protein 90 homolog; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (By similarity); Belongs to the heat shock protein 90 family
   
 
 0.899
MSI3
annotation not available
   
 
 0.857
STI1
annotation not available
   
 
 0.857
HLJ1
annotation not available
   
 
 0.840
C4YF39
annotation not available
  
 
 0.832
RPS3
annotation not available
  
 
 0.832
RPL35
annotation not available
  
 
 0.832
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 5476
Other names: ATCC 11006 [[Candida stellatoidea]], ATCC 18804, ATCC 20308, BCC 5390, BCRC 20512, C. albicans, CBS 562, CCRC 20512, Candida albicans, Candida stellatoidea, Candida stellatoidea type I, KCTC 7270, MUCL 29800, NBIMCC 72, NCAIM Y.00971, NCYC 597, NRRL Y-12983, PYCC 3436, UAMH 8765
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