STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsI_3Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)    
Predicted Functional Partners:
ptsH
Phosphocarrier protein HPr.
 0.999
fruB_1
Multiphosphoryl transfer protein.
 0.999
crr
Glucose-specific phosphotransferase enzyme IIA component.
 
 0.997
ptsG_5
PTS system N-acetylglucosamine-specific EIICBA component.
 
 0.940
ptsO
Phosphocarrier protein NPr.
 
 
 0.934
mtlA
PTS system mannitol-specific EIICBA component.
   
 0.916
bglF_2
PTS system beta-glucoside-specific EIIBCA component.
 
 
 0.908
fruA_1
PTS system fructose-specific EIIBC component.
 
  
 0.880
dhaM
PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit DhaM; Belongs to the PEP-utilizing enzyme family.
 
 
0.859
ptsN
Nitrogen regulatory protein.
 
  
 0.716
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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