STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gnd6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)    
Predicted Functional Partners:
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.998
gntK
Thermoresistant gluconokinase.
  
 0.995
rpe
Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
   
 0.954
rpiA
Ribose-5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
  
 
 0.947
pgl
6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
 
  
 0.939
ilvD_1
Phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
   
 0.923
AML35886.1
Ribose-5-phosphate isomerase B.
    
 0.919
kduD_1
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.
  
 0.850
AML38840.1
Putative oxidoreductase YgcW.
  
 0.850
ugd
UDP-glucose 6-dehydrogenase.
     
 0.847
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.