node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpA | fkpB | EAG7_02479 | EAG7_03326 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase. | 0.526 |
clpA | yecD | EAG7_02479 | EAG7_00867 | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | Putative isochorismatase family protein YecD. | 0.589 |
cmoA | cmoB | EAG7_00864 | EAG7_00863 | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | 0.997 |
cmoA | yecD | EAG7_00864 | EAG7_00867 | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | Putative isochorismatase family protein YecD. | 0.517 |
cmoA | yecE | EAG7_00864 | EAG7_00866 | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | UPF0759 protein YecE. | 0.580 |
cmoA | yecN | EAG7_00864 | EAG7_00865 | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | Inner membrane protein YecN. | 0.648 |
cmoB | cmoA | EAG7_00863 | EAG7_00864 | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | tRNA (cmo5U34)-methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). | 0.997 |
cmoB | yecD | EAG7_00863 | EAG7_00867 | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Putative isochorismatase family protein YecD. | 0.523 |
cmoB | yecE | EAG7_00863 | EAG7_00866 | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | UPF0759 protein YecE. | 0.573 |
cmoB | yecN | EAG7_00863 | EAG7_00865 | tRNA (mo5U34)-methyltransferase; Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L- methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5- carboxymethoxyuridine (cmo5U) at position 34 in tRNAs. | Inner membrane protein YecN. | 0.648 |
fkpB | clpA | EAG7_03326 | EAG7_02479 | FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase. | ATP-dependent Clp protease ATP-binding subunit ClpA; Belongs to the ClpA/ClpB family. | 0.526 |
fkpB | yecD | EAG7_03326 | EAG7_00867 | FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase. | Putative isochorismatase family protein YecD. | 0.604 |
rutA | rutC_2 | EAG7_02225 | EAG7_02227 | Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | Putative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | 0.976 |
rutA | rutD | EAG7_02225 | EAG7_02228 | Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | Putative aminoacrylate hydrolase RutD; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.967 |
rutA | rutE_1 | EAG7_02225 | EAG7_02229 | Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | Putative malonic semialdehyde reductase RutE. | 0.948 |
rutA | yecD | EAG7_02225 | EAG7_00867 | Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | Putative isochorismatase family protein YecD. | 0.647 |
rutC_2 | rutA | EAG7_02227 | EAG7_02225 | Putative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | Pyrimidine monooxygenase RutA; Catalyzes the pyrimidine ring opening between N-3 and C-4 by an unusual flavin hydroperoxide-catalyzed mechanism to yield ureidoacrylate peracid. It cleaves pyrmidine rings directly by adding oxygen atoms, making a toxic ureidoacrylate peracid product which can be spontaneously reduced to ureidoacrylate. | 0.976 |
rutC_2 | rutD | EAG7_02227 | EAG7_02228 | Putative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | Putative aminoacrylate hydrolase RutD; May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation. Belongs to the AB hydrolase superfamily. Hydrolase RutD family. | 0.996 |
rutC_2 | rutE_1 | EAG7_02227 | EAG7_02229 | Putative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | Putative malonic semialdehyde reductase RutE. | 0.911 |
rutC_2 | yecD | EAG7_02227 | EAG7_00867 | Putative aminoacrylate peracid reductase RutC; May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation. | Putative isochorismatase family protein YecD. | 0.652 |