| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| birA_2 | nnr_2 | EAG7_03886 | EAG7_03687 | Bifunctional protein BirA. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.500 |
| birA_2 | nudL | EAG7_03886 | EAG7_00980 | Bifunctional protein BirA. | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.630 |
| nnr_2 | birA_2 | EAG7_03687 | EAG7_03886 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | Bifunctional protein BirA. | 0.500 |
| nnr_2 | nudL | EAG7_03687 | EAG7_00980 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.754 |
| nnr_2 | rnr | EAG7_03687 | EAG7_03674 | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.413 |
| nudL | birA_2 | EAG7_00980 | EAG7_03886 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Bifunctional protein BirA. | 0.630 |
| nudL | nnr_2 | EAG7_00980 | EAG7_03687 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.754 |
| nudL | pabB | EAG7_00980 | EAG7_00981 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | 0.948 |
| nudL | rnr | EAG7_00980 | EAG7_03674 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | 0.443 |
| nudL | sdaA | EAG7_00980 | EAG7_00979 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.486 |
| nudL | yoaH | EAG7_00980 | EAG7_00982 | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | UPF0181 protein; Belongs to the UPF0181 family. | 0.549 |
| pabB | nudL | EAG7_00981 | EAG7_00980 | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.948 |
| pabB | sdaA | EAG7_00981 | EAG7_00979 | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.478 |
| pabB | yoaH | EAG7_00981 | EAG7_00982 | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | UPF0181 protein; Belongs to the UPF0181 family. | 0.557 |
| rnr | nnr_2 | EAG7_03674 | EAG7_03687 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | Bifunctional NAD(P)H-hydrate repair enzyme Nnr; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX; Belongs to the NnrE/AIBP family. | 0.413 |
| rnr | nudL | EAG7_03674 | EAG7_00980 | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. Belongs to the RNR ribonuclease family. RNase R subfamily. | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.443 |
| sdaA | nudL | EAG7_00979 | EAG7_00980 | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.486 |
| sdaA | pabB | EAG7_00979 | EAG7_00981 | L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | 0.478 |
| yoaH | nudL | EAG7_00982 | EAG7_00980 | UPF0181 protein; Belongs to the UPF0181 family. | Putative Nudix hydrolase NudL; Probably mediates the hydrolysis of some nucleoside diphosphate derivatives; Belongs to the Nudix hydrolase family. PCD1 subfamily. | 0.549 |
| yoaH | pabB | EAG7_00982 | EAG7_00981 | UPF0181 protein; Belongs to the UPF0181 family. | Aminodeoxychorismate synthase component 1; Part of a heterodimeric complex that catalyzes the two-step biosynthesis of 4-amino-4-deoxychorismate (ADC), a precursor of p- aminobenzoate (PABA) and tetrahydrofolate. In the first step, a glutamine amidotransferase (PabA) generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by aminodeoxychorismate synthase (PabB) to produce ADC (By similarity). | 0.557 |