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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdcCThreonine/serine transporter TdcC; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. (443 aa)    
Predicted Functional Partners:
tdcB_2
L-threonine dehydratase catabolic TdcB.
  
  
 0.801
tdcD_1
Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
  
  
 0.740
tdcE_1
PFL-like enzyme TdcE.
  
    0.622
AML34763.1
L-serine dehydratase TdcG.
 
  
 0.607
sthA
Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
      
 0.595
abgR_3
HTH-type transcriptional regulator TdcA; Belongs to the LysR transcriptional regulatory family.
  
  
 0.511
AML38580.1
Hypothetical protein.
  
     0.471
mtr
Tryptophan-specific transport protein.
  
   
 0.462
putA
Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon.
  
  
 0.434
cbpA
Curved DNA-binding protein; DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.
  
 0.423
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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