STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chbR_1HTH-type transcriptional regulator ChbR. (274 aa)    
Predicted Functional Partners:
chbC
N,N'-diacetylchitobiose permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
  
 0.894
chbA_4
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component.
     0.852
chbB
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component.
   
 0.841
chbG
UPF0249 protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6-P, the in [...]
 
   
 0.825
chbF_1
6-phospho-beta-glucosidase.
  
 0.802
nadR_3
Trifunctional NAD biosynthesis/regulator protein NadR.
  
  
 0.678
melR
Melibiose operon regulatory protein.
  
   0.669
leuO_3
Putative HTH-type transcriptional regulator LeuO; Belongs to the LysR transcriptional regulatory family.
  
    0.668
AML37504.1
Hypothetical protein.
  
     0.644
AML34899.1
Putative HTH-type transcriptional regulator YdeC.
 
   0.642
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.