Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ycdZInner membrane protein YcdZ. (140 aa)    
Predicted Functional Partners:
dcuC
Anaerobic C4-dicarboxylate transporter DcuC.
  
     0.714
ycdX
Putative phosphatase; Belongs to the PHP family.
 
   
 0.666
tyrP_2
Tyrosine-specific transport protein.
  
     0.644
AML34084.1
O-succinylbenzoate synthase.
  
     0.635
hrsA
PTS system fructose-specific EIIABC component.
      
 0.630
hcr
NADH oxidoreductase hcr.
  
     0.630
ycdY
Chaperone protein YcdY.
     
 0.605
AML36953.1
UPF0231 protein; Belongs to the UPF0231 family.
  
     0.603
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
   
 0.591
mtlA
PTS system mannitol-specific EIICBA component.
      
 0.563
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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