STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
puuDGamma-glutamyl-gamma-aminobutyrate hydrolase PuuD. (250 aa)    
Predicted Functional Partners:
puuR_1
HTH-type transcriptional regulator PuuR.
 
  
 0.960
puuC_2
Aldehyde dehydrogenase PuuC; Belongs to the aldehyde dehydrogenase family.
 
 
  0.947
AML35262.1
Hypothetical protein.
     0.927
prr
Gamma-aminobutyraldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
  
 
  0.907
AML38540.1
Aldehyde dehydrogenase PuuC.
  
 
  0.907
AML35995.1
4-aminobutyrate aminotransferase PuuE.
 
 
 0.897
glnA
Glutamine synthetase.
  
 
 0.896
puuB_2
Gamma-glutamylputrescine oxidoreductase.
 
  
 0.877
puuA_2
Gamma-glutamylputrescine synthetase PuuA; Belongs to the glutamine synthetase family.
 
  
 0.874
gabT
4-aminobutyrate aminotransferase GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
 
 0.834
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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