Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AML36150.1Hypothetical protein. (478 aa)    
Predicted Functional Partners:
AML36148.1
Protein CyaD.
 
 0.984
AML36149.1
Exotoxin translocation ATP-binding protein PaxB.
  
 0.981
AML36152.1
Hypothetical protein.
 
   
 0.914
AML36151.1
Hypothetical protein.
       0.762
AML36147.1
Putative poly(glycerol-phosphate) alpha-glucosyltransferase.
 
     0.739
tolC_2
Outer membrane protein TolC.
     
 0.677
ttgA
Multidrug resistance protein MdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.671
macA_1
Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
  
 0.671
macB
Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.613
yibH_4
Putative multidrug resistance protein EmrK.
  
 
 0.572
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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