Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ompAOuter membrane protein A; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. (358 aa)    
Predicted Functional Partners:
ompC
Outer membrane protein C; Belongs to the Gram-negative porin family.
  
 0.978
skp
Chaperone protein Skp; Belongs to the skp family.
  
 
 0.957
pal
Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.956
ompF
Outer membrane protein F.
  
 0.932
degP_3
Periplasmic serine endoprotease DegP.
   
 
 0.927
degQ
Periplasmic pH-dependent serine endoprotease DegQ; Belongs to the peptidase S1C family.
   
 
 0.890
AML36978.1
Protein translocase subunit SecA.
   
 
 0.873
yaeT_1
Outer membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery.
 
 
 0.858
ompX
Outer membrane protein X.
   
 
 0.830
phoE
Outer membrane pore protein E; Belongs to the Gram-negative porin family.
  
 0.822
Your Current Organism:
Klebsiella aerogenes
NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006
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