pflA_1 protein (Klebsiella aerogenes) - STRING interaction network

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pflA_1

Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa)

Predicted Functional Partners:

pflB_4

0.964

tdcE_1

0.928

csdB

0.864

AML37227.1

0.808

focA

0.805

grcA

0.787

ykfG

0.654

AML38998.1

0.654

yxeP_5

0.643

yxeP_1

0.643

Your Current Organism:

Klebsiella aerogenes

NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AML37227.1	grcA	EAG7_03484	EAG7_05371	Formate acetyltransferase 2.	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.888
AML37227.1	pflA_1	EAG7_03484	EAG7_02464	Formate acetyltransferase 2.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.808
AML38998.1	pflA_1	EAG7_05268	EAG7_02464	UPF0758 protein YkfG.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.654
AML38998.1	yxeP_1	EAG7_05268	EAG7_01955	UPF0758 protein YkfG.	Hippurate hydrolase.	0.693
AML38998.1	yxeP_5	EAG7_05268	EAG7_01205	UPF0758 protein YkfG.	Hippurate hydrolase.	0.693
csdB	grcA	EAG7_02547	EAG7_05371	Putative formate acetyltransferase 3.	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.805
csdB	pflA_1	EAG7_02547	EAG7_02464	Putative formate acetyltransferase 3.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.864
focA	pflA_1	EAG7_02462	EAG7_02464	Putative formate transporter 1.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.805
focA	pflB_4	EAG7_02462	EAG7_02463	Putative formate transporter 1.	Formate acetyltransferase 1.	0.802
focA	tdcE_1	EAG7_02462	EAG7_01016	Putative formate transporter 1.	PFL-like enzyme TdcE.	0.485
grcA	AML37227.1	EAG7_05371	EAG7_03484	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Formate acetyltransferase 2.	0.888
grcA	csdB	EAG7_05371	EAG7_02547	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Putative formate acetyltransferase 3.	0.805
grcA	pflA_1	EAG7_05371	EAG7_02464	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.787
grcA	pflB_4	EAG7_05371	EAG7_02463	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Formate acetyltransferase 1.	0.817
grcA	tdcE_1	EAG7_05371	EAG7_01016	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	PFL-like enzyme TdcE.	0.817
pflA_1	AML37227.1	EAG7_02464	EAG7_03484	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Formate acetyltransferase 2.	0.808
pflA_1	AML38998.1	EAG7_02464	EAG7_05268	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	UPF0758 protein YkfG.	0.654
pflA_1	csdB	EAG7_02464	EAG7_02547	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Putative formate acetyltransferase 3.	0.864
pflA_1	focA	EAG7_02464	EAG7_02462	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Putative formate transporter 1.	0.805
pflA_1	grcA	EAG7_02464	EAG7_05371	Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Autonomous glycyl radical cofactor; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.787

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