| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dadB | lrp | EAG7_01003 | EAG7_02473 | Alanine racemase, catabolic; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | 0.598 |
| dadB | nac | EAG7_01003 | EAG7_00767 | Alanine racemase, catabolic; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Nitrogen assimilation regulatory protein nac; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression. | 0.674 |
| dadB | putA | EAG7_01003 | EAG7_02222 | Alanine racemase, catabolic; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon. | 0.536 |
| ftsK | lolA | EAG7_02472 | EAG7_02471 | DNA translocase FtsK. | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.875 |
| ftsK | lrp | EAG7_02472 | EAG7_02473 | DNA translocase FtsK. | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | 0.819 |
| ftsK | rarA | EAG7_02472 | EAG7_02470 | DNA translocase FtsK. | Replication-associated recombination protein A. | 0.866 |
| gltB | lrp | EAG7_04600 | EAG7_02473 | Glutamate synthase [NADPH] large chain. | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | 0.495 |
| gltB | putA | EAG7_04600 | EAG7_02222 | Glutamate synthase [NADPH] large chain. | Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon. | 0.945 |
| lolA | ftsK | EAG7_02471 | EAG7_02472 | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | DNA translocase FtsK. | 0.875 |
| lolA | lrp | EAG7_02471 | EAG7_02473 | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | 0.792 |
| lolA | rarA | EAG7_02471 | EAG7_02470 | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Replication-associated recombination protein A. | 0.935 |
| lrp | dadB | EAG7_02473 | EAG7_01003 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Alanine racemase, catabolic; Isomerizes L-alanine to D-alanine which is then oxidized to pyruvate by DadA. | 0.598 |
| lrp | ftsK | EAG7_02473 | EAG7_02472 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | DNA translocase FtsK. | 0.819 |
| lrp | gltB | EAG7_02473 | EAG7_04600 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Glutamate synthase [NADPH] large chain. | 0.495 |
| lrp | lolA | EAG7_02473 | EAG7_02471 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Outer-membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.792 |
| lrp | nac | EAG7_02473 | EAG7_00767 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Nitrogen assimilation regulatory protein nac; Transcriptional activator for the hut, put and ure operons and repressor for the gdh and gltB operons in response to nitrogen limitation. Negative regulator of its own expression. | 0.435 |
| lrp | putA | EAG7_02473 | EAG7_02222 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Bifunctional protein PutA; Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon. | 0.495 |
| lrp | rarA | EAG7_02473 | EAG7_02470 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Replication-associated recombination protein A. | 0.762 |
| lrp | rpoS | EAG7_02473 | EAG7_05128 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | RNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. | 0.427 |
| lrp | seqA | EAG7_02473 | EAG7_02683 | Leucine-responsive regulatory protein; Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes (By similarity). | Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.477 |