macB protein (Klebsiella aerogenes) - STRING interaction network

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macB

Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)

Predicted Functional Partners:

macA_1

0.998

acrA_2

0.917

mexA

0.888

acrA_1

0.886

ttgA

0.868

bepF_1

0.868

cusB_3

0.868

AML37452.1

0.852

rsmA

0.839

tolC_2

0.835

Your Current Organism:

Klebsiella aerogenes

NCBI taxonomy Id: 548
Other names: ATCC 13048, Aerobacter aerogenes, CIP 60.86, DSM 30053, Enterobacter aerogenes, HAMBI 101, IFO 13534, K. aerogenes, KCTC 2190, Klebsiella mobilis, LMG 2094, LMG:2094, NBRC 13534, NCAIM B.01467, NCTC 10006

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AML37452.1	acrA_1	EAG7_03711	EAG7_04557	Microcin H47 secretion protein MchE.	Multidrug export protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.465
AML37452.1	macB	EAG7_03711	EAG7_02482	Microcin H47 secretion protein MchE.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.852
AML37452.1	mexA	EAG7_03711	EAG7_04169	Microcin H47 secretion protein MchE.	Multidrug resistance protein MexA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.462
AML37452.1	tolC_2	EAG7_03711	EAG7_04777	Microcin H47 secretion protein MchE.	Outer membrane protein TolC.	0.644
acrA_1	AML37452.1	EAG7_04557	EAG7_03711	Multidrug export protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Microcin H47 secretion protein MchE.	0.465
acrA_1	macB	EAG7_04557	EAG7_02482	Multidrug export protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.886
acrA_1	tolC_2	EAG7_04557	EAG7_04777	Multidrug export protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.611
acrA_2	macB	EAG7_02903	EAG7_02482	Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.917
acrA_2	mexA	EAG7_02903	EAG7_04169	Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug resistance protein MexA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.905
acrA_2	tolC_2	EAG7_02903	EAG7_04777	Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.993
bepF_1	macB	EAG7_02110	EAG7_02482	Efflux pump periplasmic linker BepF; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.868
bepF_1	tolC_2	EAG7_02110	EAG7_04777	Efflux pump periplasmic linker BepF; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.560
cusB_3	macB	EAG7_03503	EAG7_02482	Cation efflux system protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.868
cusB_3	tolC_2	EAG7_03503	EAG7_04777	Cation efflux system protein CusB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.502
macA_1	macB	EAG7_02483	EAG7_02482	Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.998
macA_1	tolC_2	EAG7_02483	EAG7_04777	Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Outer membrane protein TolC.	0.984
macA_1	ttgA	EAG7_02483	EAG7_00537	Macrolide export protein MacA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Multidrug resistance protein MdtA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.575
macB	AML37452.1	EAG7_02482	EAG7_03711	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Microcin H47 secretion protein MchE.	0.852
macB	acrA_1	EAG7_02482	EAG7_04557	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Multidrug export protein AcrE; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.886
macB	acrA_2	EAG7_02482	EAG7_02903	Macrolide export ATP-binding/permease protein MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	Multidrug efflux pump subunit AcrA; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.917

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