| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fabG_12 | moaF | EAG7_02825 | EAG7_02826 | Protein MoaE. | Protein MoaF. | 0.898 |
| gcvP | guaA_1 | EAG7_04916 | EAG7_00168 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.536 |
| gcvP | moaF | EAG7_04916 | EAG7_02826 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Protein MoaF. | 0.945 |
| gcvP | purC | EAG7_04916 | EAG7_00196 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.768 |
| gcvP | purF | EAG7_04916 | EAG7_00288 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.815 |
| gcvP | purH | EAG7_04916 | EAG7_03853 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Bifunctional purine biosynthesis protein PurH. | 0.803 |
| gcvP | purL | EAG7_04916 | EAG7_05393 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.952 |
| gcvP | purM | EAG7_04916 | EAG7_00183 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.414 |
| gcvP | purN | EAG7_04916 | EAG7_00181 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.435 |
| guaA_1 | gcvP | EAG7_00168 | EAG7_04916 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.536 |
| guaA_1 | moaF | EAG7_00168 | EAG7_02826 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Protein MoaF. | 0.815 |
| guaA_1 | purC | EAG7_00168 | EAG7_00196 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family. | 0.664 |
| guaA_1 | purF | EAG7_00168 | EAG7_00288 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.826 |
| guaA_1 | purH | EAG7_00168 | EAG7_03853 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Bifunctional purine biosynthesis protein PurH. | 0.870 |
| guaA_1 | purK_2 | EAG7_00168 | EAG7_02871 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | N5-carboxyaminoimidazole ribonucleotide synthase. | 0.647 |
| guaA_1 | purL | EAG7_00168 | EAG7_05393 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.980 |
| guaA_1 | purM | EAG7_00168 | EAG7_00183 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.666 |
| guaA_1 | purN | EAG7_00168 | EAG7_00181 | GMP synthase glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.517 |
| moaF | fabG_12 | EAG7_02826 | EAG7_02825 | Protein MoaF. | Protein MoaE. | 0.898 |
| moaF | gcvP | EAG7_02826 | EAG7_04916 | Protein MoaF. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |