| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahcY | luxS | EAG7_00660 | EAG7_05202 | Adenosylhomocysteinase. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.930 |
| ahcY | metB_3 | EAG7_00660 | EAG7_03910 | Adenosylhomocysteinase. | Cystathionine gamma-synthase. | 0.917 |
| ahcY | metC_1 | EAG7_00660 | EAG7_04797 | Adenosylhomocysteinase. | Cystathionine beta-lyase MetC. | 0.917 |
| ahcY | metE | EAG7_00660 | EAG7_03992 | Adenosylhomocysteinase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.969 |
| ahcY | metH | EAG7_00660 | EAG7_03845 | Adenosylhomocysteinase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.971 |
| ahcY | metK | EAG7_00660 | EAG7_04869 | Adenosylhomocysteinase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.856 |
| ahcY | mmuM | EAG7_00660 | EAG7_03034 | Adenosylhomocysteinase. | Homocysteine S-methyltransferase. | 0.915 |
| ahcY | xecA1 | EAG7_00660 | EAG7_02787 | Adenosylhomocysteinase. | Putative methylcobalamin:homocysteine methyltransferase. | 0.962 |
| luxS | ahcY | EAG7_05202 | EAG7_00660 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Adenosylhomocysteinase. | 0.930 |
| luxS | metB_3 | EAG7_05202 | EAG7_03910 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Cystathionine gamma-synthase. | 0.940 |
| luxS | metC_1 | EAG7_05202 | EAG7_04797 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Cystathionine beta-lyase MetC. | 0.943 |
| luxS | metE | EAG7_05202 | EAG7_03992 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.930 |
| luxS | metH | EAG7_05202 | EAG7_03845 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.971 |
| luxS | mmuM | EAG7_05202 | EAG7_03034 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Homocysteine S-methyltransferase. | 0.910 |
| luxS | xecA1 | EAG7_05202 | EAG7_02787 | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | Putative methylcobalamin:homocysteine methyltransferase. | 0.938 |
| lysP_2 | mmuM | EAG7_03035 | EAG7_03034 | Putative S-methylmethionine permease. | Homocysteine S-methyltransferase. | 0.934 |
| metB_3 | ahcY | EAG7_03910 | EAG7_00660 | Cystathionine gamma-synthase. | Adenosylhomocysteinase. | 0.917 |
| metB_3 | luxS | EAG7_03910 | EAG7_05202 | Cystathionine gamma-synthase. | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.940 |
| metB_3 | metC_1 | EAG7_03910 | EAG7_04797 | Cystathionine gamma-synthase. | Cystathionine beta-lyase MetC. | 0.970 |
| metB_3 | metE | EAG7_03910 | EAG7_03992 | Cystathionine gamma-synthase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.962 |
