| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ilvE | lysC | EAG7_04045 | EAG7_03830 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.492 |
| ilvE | metB_3 | EAG7_04045 | EAG7_03910 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Cystathionine gamma-synthase. | 0.927 |
| ilvE | metC_2 | EAG7_04045 | EAG7_01641 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Cystathionine beta-lyase. | 0.916 |
| ilvE | metH | EAG7_04045 | EAG7_03845 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.579 |
| ilvE | metL_1 | EAG7_04045 | EAG7_03909 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Bifunctional aspartokinase/homoserine dehydrogenase 2. | 0.927 |
| ilvE | thrA | EAG7_04045 | EAG7_03362 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.936 |
| ilvE | thrB | EAG7_04045 | EAG7_03361 | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.840 |
| lysC | ilvE | EAG7_03830 | EAG7_04045 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Branched-chain-amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.492 |
| lysC | metA | EAG7_03830 | EAG7_03851 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | 0.468 |
| lysC | metH | EAG7_03830 | EAG7_03845 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.581 |
| lysC | metL_1 | EAG7_03830 | EAG7_03909 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Bifunctional aspartokinase/homoserine dehydrogenase 2. | 0.962 |
| lysC | thrA | EAG7_03830 | EAG7_03362 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.966 |
| lysC | thrB | EAG7_03830 | EAG7_03361 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.919 |
| lysC | thrC | EAG7_03830 | EAG7_03360 | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | Threonine synthase. | 0.888 |
| metA | lysC | EAG7_03851 | EAG7_03830 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Lysine-sensitive aspartokinase 3; Belongs to the aspartokinase family. | 0.468 |
| metA | metB_3 | EAG7_03851 | EAG7_03910 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Cystathionine gamma-synthase. | 0.986 |
| metA | metC_2 | EAG7_03851 | EAG7_01641 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Cystathionine beta-lyase. | 0.762 |
| metA | metH | EAG7_03851 | EAG7_03845 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.909 |
| metA | metL_1 | EAG7_03851 | EAG7_03909 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Bifunctional aspartokinase/homoserine dehydrogenase 2. | 0.971 |
| metA | thrA | EAG7_03851 | EAG7_03362 | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. | Bifunctional aspartokinase/homoserine dehydrogenase 1; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.975 |